|Official Full Name||sphingosine-1-phosphate receptor 3|
|Background||This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008]|
|Synonyms||S1PR3; sphingosine-1-phosphate receptor 3; EDG3; LPB3; S1P3; EDG-3; sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P receptor EDG3; S1P receptor Edg-3; sphingosine 1-phosphate receptor Edg-3; endothelial differentiation G-protein coupled receptor 3; G protein-coupled receptor, endothelial differentiation gene-3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
S1PR3 involved in several pathways and played different roles in them. We selected most pathways S1PR3 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with S1PR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Class A/1 (Rhodopsin-like receptors)||DRD4; TRH; CXCR6; ADRB3; NMB; PROKR1A; ADRB2; CHRM4; PRLH; CXCR7B|
|G alpha (i) signalling events||CCL27; PPY; OXGR1; DRD2; APPB; OPN1MW; LPAR2B; SSTR5; SSTR4; CCL35.1|
|GPCR downstream signaling||GPR132B; RGS6; PROKR1; OXGR1A.1; TRPC3; CCR7; RGS17; GPR18; PNOCB; RGS1|
|GPCR ligand binding||ANXA1; ADCYAP1; XK; CCL35.2; SCT; OPN4A; ADM; S1PR5B; CRHB; GPR132|
|Lysosphingolipid and LPA receptors||S1PR3; LPAR2A; S1PR1; S1PR5B; LPAR5A; LPAR2B|
|Neuroactive ligand-receptor interaction||CCKBR; F2R; PTGER4A; TAAR14J; PRL2; Gh; GIPR; TAAR12H; GRIK4; VIPR1|
|Signal Transduction||SOX9A; LINGO1B; GPR55A; NMT1B; CCL19A.2; CCK; XK; TLE4; APLNR; FGD2|
S1PR3 has several biochemical functions, for example, G-protein coupled receptor activity, integrin binding, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S1PR3 itself. We selected most functions S1PR3 had, and list some proteins which have the same functions with S1PR3. You can find most of the proteins on our site.
|G-protein coupled receptor activity||NPFFR1; PTGIR; GRM3; VALOPB; S1PR3A; TAS2R106; GPR98; DRD1B; GPR81; GPR25|
|integrin binding||ACTN3; ADAM10; EMP2; Npnt; WISP1B; FAP; PXN; EDIL3; S1PR3; ICAM2|
|lipid binding||S100A13; RASGRP1; PAQR7B; BPIFB1; APOA4A; APOE; PTEN; BPIFA5; CRABP1B; FAM125A|
|protein binding||REV1; TMEM106B; RRAS2; CEACAM6; IL12A; NAPG; HNRNPH2; INPP4B; GSN; TBC1D1|
|sphingosine-1-phosphate receptor activity||S1PR4; S1PR3; S1PR2; SPHK2; GPR6; S1PR3A; S1PR1; S1PR5; S1PR5A; SPHK1|
S1PR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S1PR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of S1PR3.