This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development.
SCML2; sex comb on midleg-like 2 (Drosophila); sex comb on midleg (Drosophila) like 2; sex comb on midleg-like protein 2
SCML2 has several biochemical functions, for example, DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SCML2 itself. We selected most functions SCML2 had, and list some proteins which have the same functions with SCML2. You can find most of the proteins on our site.
Function DNA binding
Related Protein HNF1BA; ZNF599; GABPA; HOXD13; PDS5B; ZNF729; RXRGA; POU2F1A; E2F1; ZNF710
Function transcription factor activity, sequence-specific DNA binding
Related Protein ZKSCAN5; FOXA; CDX2; RBPJA; MYCLA; RFXANK; KLF17; ZRANB2; SMAD2; CEBP1
SCML2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCML2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SCML2.