scn1b
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  • Official Full Name
  • sodium channel, voltage-gated, type I, beta subunit
  • Background
  • SCN1B is a single-pass type I membrane protein abundantly expressed in skeletal muscle, heart and brain. The SCN1B forms part of a heterotrimeric complex of voltage-gated sodium channels involved in the generation and propagation of action potentials in m
  • Synonyms
  • SCN1B; sodium channel, voltage-gated, type I, beta subunit; sodium channel, voltage gated, type I, beta , sodium channel, voltage gated, type I, beta polypeptide; sodium channel subunit beta-1; sodium channel beta-1 subunit; GEFSP1
Cat.#:SCN1B-2535HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SCN1B, GST-tagged
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Cat.#:SCN1B-14754MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SCN1B Protein
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Cat.#:SCN1B-5261RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SCN1B Protein
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Cat.#:SCN1B-4099RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SCN1B Protein, His-tagged
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Cat.#:SCN1B-2031HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SCN1B 293 Cell Lysate
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Involved Pathway

SCN1B involved in several pathways and played different roles in them. We selected most pathways SCN1B participated on our site, such as Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCN1B were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adrenergic signaling in cardiomyocytes
TPM4; PLCB1; SCN5A; CALM3; ADRA1B; CACNB3; ADRB2A; GNAI3; ADRB2; KCNQ1

Protein Function

SCN1B has several biochemical functions, for example, sodium channel inhibitor activity, sodium channel regulator activity, voltage-gated sodium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCN1B itself. We selected most functions SCN1B had, and list some proteins which have the same functions with SCN1B. You can find most of the proteins on our site.
Function
Related Protein
Function sodium channel inhibitor activity
Related Protein SCN1B; PCSK9; NEDD4; CAMK2D; NEDD4L; SLC14A2
Function sodium channel regulator activity
Related Protein FGF12; YWHAH; FXYD6; PTPN3; NEDD4L; RANGRF; CAV3; NOS1; SGK2; FXYD7
Function voltage-gated sodium channel activity
Related Protein SCN11A; HCN4; SCN12AB; PKD2; SCN9A; ASIC4A; HCN2; SCN5A; SCN8AB; SCN1B
Function voltage-gated sodium channel activity involved in Purkinje myocyte action potential
Related Protein SCN1B; SCN5A
Function voltage-gated sodium channel activity involved in cardiac muscle cell action potential
Related Protein SCN5A; SCN1B; SCN2B; SCN3B

SCN1B Related Articles

Casini, S; Tan, HL; et al. Tubulin polymerization modifies cardiac sodium channel expression and gating. CARDIOVASCULAR RESEARCH 85:691-700(2010).