SEC63 Protein, SEC63 homolog (S. cerevisiae)


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Official Full Name SEC63 homolog (S. cerevisiae)
Background The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Synonyms SEC63; SEC63 homolog (S. cerevisiae); SEC63 like (S. cerevisiae); translocation protein SEC63 homolog; DNAJC23; ERdj2; PRO2507; SEC63L; SEC 63
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Sec63-1003M Recombinant Mouse Sec63 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human SEC63-1988HCL Recombinant Human SEC63 293 Cell Lysate HEK293 N/A
    Human SEC63-2569H Recombinant Human SEC63, His-tagged E.coli His
    Mouse SEC63-14843M Recombinant Mouse SEC63 Protein Mammalian Cell His
    Rhesus Macaque SEC63-4130R Recombinant Rhesus monkey SEC63 Protein, His-tagged Mammalian Cell His
    Zebrafish SEC63-706Z Recombinant Zebrafish SEC63 Mammalian Cell His

    SEC63 involved in several pathways and played different roles in them. We selected most pathways SEC63 participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Protein export, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC63 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    IRE1alpha activates chaperones CXXC1; YIF1A; SEC61B; C19orf10; TPP1; DDX11; ADD1; SEC63; PDIA6; DNAJB9
    Metabolism of proteins DOHH; TRAPPC4; GNE; GATA6; ST6GALNAC1.2; TRAPPC2L; PFDN4; TIMM50; EIF2B1; PHC2
    Protein export SRPRB; SRP54A; IMMP2L; SPCS1; SRP68; HSPA5; SEC61G; ARXES1; SRP54; SLC38A8
    Protein processing in endoplasmic reticulum EIF2S1B; LMAN1; HSPA8; EDEM1; SELS; DNAJC5GA; SEC13; RAD23B; HSP70; BCL2A
    Unfolded Protein Response (UPR) HDGF; YIF1A; DNAJB9; YY2; C19orf10; KLHDC3; WIPI1; SEC63; TPP1; SERP1
    XBP1(S) activates chaperone genes PDIA6; TPP1; CTDSP2; WIPI1; CXXC1; KLHDC3; DDX11; SERP1; YIF1A; SEC63

    SEC63 has several biochemical functions, for example, poly(A) RNA binding, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC63 itself. We selected most functions SEC63 had, and list some proteins which have the same functions with SEC63. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding ZC3H10; MRPL3; ZC3H18; SLC25A5; PNO1; XRN2; RPS12; SART1; TPR; RPUSD3
    protein binding TCF7L2; PMM2; DHX32; DMD; PDE2A; RBM3; PMM1; ZFYVE28; TCF3; IL15
    receptor activity MED13; PVR; KLRB1B; SEMA4D; GRIN1A; KLRC4-KLRK1; APLNR; AMFR; PAQR5B; V1RA8

    SEC63 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC63 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC63.

    Nxn; PTP4A3; MCC; HLA-B; MAGEA6; MDM2; GSTK1; PHLDA3; NXN; cutF; 15-deoxy-delta(12,14; Irf1; Bub1b

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