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SEPT12

Official Full Name

septin 12
Overview

This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

SEPT12; septin 12; septin-12; FLJ25410; SEPT12; SEP12_HUMAN; Septin-12; Septin12;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SEPT12-1964HCL	Recombinant Human SEPT12 293 Cell Lysate	HEK293	N/A	Inquiry
Rat	SEPT12-5324R	Recombinant Rat SEPT12 Protein	Mammalian Cell	His	Inquiry
Rat	SEPT12-4983R	Recombinant Rat SEPT12 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	SEPT12-4983R-B	Recombinant Rat SEPT12 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

SEPT12 involved in several pathways and played different roles in them. We selected most pathways SEPT12 participated on our site, such as Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEPT12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Bacterial invasion of epithelial cells	SEPT2;RHOA;ARPC3;PXN;SHC3;CDC42;GAB1;HCLS1;FN1

SEPT12 has several biochemical functions, for example, GDP binding, GTP binding, phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEPT12 itself. We selected most functions SEPT12 had, and list some proteins which have the same functions with SEPT12. You can find most of the proteins on our site.

Function	Related Protein
GDP binding	RRAGC;PIGC;RAP1B;GNAI1;RAB18;RAB27B;KRAS;RAB8A;TRIM23
GTP binding	TUBA4L;RAB4A;RAB2A;ARL14;REM1;GNAO1B;RAB1BB;ARFIP2;GTPBP8
phosphatidylinositol binding	SNX1A;TULP4A;SNX32;MYO1E;ARHGAP32;PIK3C2G;ING2;SNX17;SNX9B
protein binding	CKB;PDE6D;PHAX;GATA6;DNAJB5;NDUFAF1;NEFM;ADI1;PDK1
protein homodimerization activity	SDS;SRGAP2A;CHMP4A;ATF3;PLCB1;NPPC;YARS2;MASP1;MECOM

SEPT12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEPT12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEPT12.

SEPT6; SPAG4; SEPT1; LMNB1; SEPT4; OBSL1; PRM2; PCM1; NDC1