sept12
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  • Official Full Name
  • septin 12
  • Background
  • This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • SEPT12; septin 12; septin-12; FLJ25410; SEPT12; SEP12_HUMAN; Septin-12; Septin12
Cat.#:SEPT12-5324RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SEPT12 Protein
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Cat.#:SEPT12-1964HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SEPT12 293 Cell Lysate
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Involved Pathway

SEPT12 involved in several pathways and played different roles in them. We selected most pathways SEPT12 participated on our site, such as Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEPT12 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Bacterial invasion of epithelial cells
PIK3CA; ELMO2; GAB1; DNM1; CDH1; ARPC1A; SEPT3; CDC42; PTK2; MET

Protein Function

SEPT12 has several biochemical functions, for example, GDP binding, GTP binding, phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEPT12 itself. We selected most functions SEPT12 had, and list some proteins which have the same functions with SEPT12. You can find most of the proteins on our site.
Function
Related Protein
Function GDP binding
Related Protein RHOB; RAB8A; RAB21; RAB8B; RAB14; RAN; ARL2; PRPS2; RALB; SRP54B
Function GTP binding
Related Protein TUBA8L4; SPAG1; IRGC; TPX2; MXC; TUBB4B; IIGP1; SRPRB; TUBA8L3; RAB18B
Function phosphatidylinositol binding
Related Protein PXK; PIK3C2A; GRB7; SNX9B; SH3YL1; NISCH; ARHGAP32; ZCCHC2; TNFAIP8L3; SNX17
Function protein binding
Related Protein BNIP3; NUP155; HNRNPM; APBB1; ENTPD3; ZNF335; ASCL3; GALR2; TPP2; RASSF9
Function protein homodimerization activity
Related Protein HLA-G; ATP2A1; NR4A3; STK25; NR2F2; TCF3B; APOA2; ABCG1; MTMR2; TRIM9

Interacting Protein

SEPT12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEPT12 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEPT12.
SEPT6; SPAG4; SEPT1; LMNB1; SEPT4; OBSL1; PRM2; PCM1; NDC1