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SEPT9

Official Full Name

septin 9
Overview

This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms

SEPT9; septin 9; MLL septin like fusion , MSF; septin-9; AF17q25; KIAA0991; MSF1; Ov/Br septin; PNUTL4; SeptD1; AF17q25; Cell division control protein septin D1; KIAA0991; MLL septin like fusion protein; MLL septin-like fusion protein; MLL septin-like fusion protein MSF-A; MSF; MSF1; Ov/Br septin; Ovarian/breast septin alpha; Ovarian/Breast septin; PNUTL4; SEPT9; SEPT9_HUMAN; Septin 9; Septin D1; Septin-9; SINT1; septin D1; ovarian/breast septin; MLL septin-like fusion protein MSF-A; MSF; NAPB; SINT1;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SEPT9-1952HCL	Recombinant Human SEPT9 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SEPT9-2601H	Recombinant Human SEPT9 protein, His-tagged	E.coli	His	250-568 aa	$319 / 25ug
Mouse	SEPT9-14899M	Recombinant Mouse SEPT9 Protein	Mammalian Cell	His		Inquiry
Mouse	SEPT9-8030M	Recombinant Mouse SEPT9 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	SEPT9-2421M	Recombinant Mouse SEPT9 Protein (1-583 aa), His-tagged	E.coli	His	1-583 aa	Inquiry
Mouse	SEPT9-8030M-B	Recombinant Mouse SEPT9 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	SEPT9-5328R	Recombinant Rat SEPT9 Protein	Mammalian Cell	His		Inquiry
Rat	SEPT9-4987R	Recombinant Rat SEPT9 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SEPT9-4987R-B	Recombinant Rat SEPT9 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	SEPT9-2404C	Recombinant Chicken SEPT9	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SEPT9 Related Articles

SEPT9 involved in several pathways and played different roles in them. We selected most pathways SEPT9 participated on our site, such as Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEPT9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Bacterial invasion of epithelial cells	ACTB;ARPC5L;ARPC3;ITGA5;SRC;SHC2;PIK3CD;ARPC5;CDC42

SEPT9 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEPT9 itself. We selected most functions SEPT9 had, and list some proteins which have the same functions with SEPT9. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	EIF2S3;RASEF;RHEB;TUBB;EHD2B;TUBA7L;RAB39B;ARL4A;ARL13A
GTPase activity	RAB1;GNG10;ARL8B;RAB3B;ATL2;GNA12A;DNAJC27;RAB42;GNA11
protein binding	CCDC59;OSBPL2;PHC3;TPD52L1;ATRIP;STAU2;NAA30;CST7;MYBPH

SEPT9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEPT9 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEPT9.

SEPT6; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; IKBKG; DDA1; TRAF6; STK11; pi3p; Sept7; ssdna_dtdc; Calu; PTBP3; FN1

Stanbery, L; D'Silva, NJ; et al. High SEPT9_v1 Expression Is Associated with Poor Clinical Outcomes in Head and Neck Squamous Cell Carcinoma. TRANSLATIONAL ONCOLOGY 3:239-245(2010).

Tachibana, T; Okazaki, E; et al. Rat Monoclonal Antibody Specific for Septin 9. HYBRIDOMA 29:169-171(2010).