sept9
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  • Official Full Name
  • septin 9
  • Background
  • This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms
  • SEPT9; septin 9; MLL septin like fusion , MSF; septin-9; AF17q25; KIAA0991; MSF1; Ov/Br septin; PNUTL4; SeptD1; AF17q25; Cell division control protein septin D1; KIAA0991; MLL septin like fusion protein; MLL septin-like fusion protein; MLL septin-like fusion protein MSF-A; MSF; MSF1; Ov/Br septin; Ovarian/breast septin alpha; Ovarian/Breast septin; PNUTL4; SEPT9; SEPT9_HUMAN; Septin 9; Septin D1; Septin-9; SINT1; septin D1; ovarian/breast septin; MLL septin-like fusion protein MSF-A; MSF; NAPB; SINT1
Cat.#:SEPT9-2421MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse SEPT9 Protein (1-583 aa), His-tagged
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Cat.#:SEPT9-14899MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SEPT9 Protein
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Cat.#:SEPT9-5328RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SEPT9 Protein
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Cat.#:SEPT9-2404CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SEPT9
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Cat.#:SEPT9-1952HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SEPT9 293 Cell Lysate
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Involved Pathway

SEPT9 involved in several pathways and played different roles in them. We selected most pathways SEPT9 participated on our site, such as Bacterial invasion of epithelial cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEPT9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Bacterial invasion of epithelial cells
ITGA5; CAV2; SHC1; ARPC1B; GAB1; PXN; RHOA; BCAR1; DOCK1; SEPT9

Protein Function

SEPT9 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEPT9 itself. We selected most functions SEPT9 had, and list some proteins which have the same functions with SEPT9. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein MFN1; RASL11B; NRAS; ARL14; EEF1A1B; EFTUD2; SAR1AB; RSG1; GIMAP6; RERGL
Function GTPase activity
Related Protein SEPT9; RAB7; RHEB; DNM2B; TUBA3D; RALBA; RAB28; RNF112; RAB39A; ATL1
Function protein binding
Related Protein HMOX1; SH3RF2; CASQ2; RPLP1; ADM; FAM118B; UHMK1; CCBL1; EIF4A1; ASUN

Interacting Protein

SEPT9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEPT9 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEPT9.
SEPT6; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; IKBKG; DDA1; TRAF6; STK11; pi3p; Sept7; ssdna_dtdc; Calu; PTBP3; FN1

SEPT9 Related Articles

Stanbery, L; D'Silva, NJ; et al. High SEPT9_v1 Expression Is Associated with Poor Clinical Outcomes in Head and Neck Squamous Cell Carcinoma. TRANSLATIONAL ONCOLOGY 3:239-245(2010).
Tachibana, T; Okazaki, E; et al. Rat Monoclonal Antibody Specific for Septin 9. HYBRIDOMA 29:169-171(2010).