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Official Full Name splicing factor 3B, 14 kDa subunit
Background This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
Synonyms SF3B14; splicing factor 3B, 14 kDa subunit; pre-mRNA branch site protein p14; SF3b 14 kDa subunit; spliceosome-associated protein, 14 kDa subunit; P14; Ht006; SAP14; CGI-110; HSPC175; SF3B14a
    • Species :
    • Human
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SF3B14-1918HCL Recombinant Human SF3B14 293 Cell Lysate HEK293 N/A
    Human SF3B14-3411H Recombinant Human SF3B14, His-tagged E.coli His
    Rhesus Macaque SF3B14-4169R Recombinant Rhesus monkey SF3B14 Protein, His-tagged Mammalian Cell His

    SF3B14 involved in several pathways and played different roles in them. We selected most pathways SF3B14 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with SF3B14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spliceosome PRPF6; TTC6; ISY1; RBM8A; HNRNPUB; SNRPB; USP39; SNW1; LSM8; SNRNP70

    SF3B14 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by SF3B14 itself. We selected most functions SF3B14 had, and list some proteins which have the same functions with SF3B14. You can find most of the proteins on our site.

    Function Related Protein
    nucleotide binding JAK2B; HSPA4A; ATP8B5; GSK3AA; KIF4; WRNIP1; MYH1; CSNK1G2B; FGFR1B; ABCG2A
    poly(A) RNA binding FAM120A; RPUSD4; RPP25L; MRPL4; HNRNPF; SF3A3; FMR1; ZC3H8; SLC25A5; CCDC55

    SF3B14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SF3B14 here. Most of them are supplied by our site. Hope this information will be useful for your research of SF3B14.

    Paun, BC; Kukuruga, D; et al. Relation Between Normal Rectal Methylation, Smoking Status, and the Presence or Absence of Colorectal Adenomas. CANCER 116:4495-4501(2010).

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