sf3b14
Share
  • Official Full Name
  • splicing factor 3B, 14 kDa subunit
  • Background
  • This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
  • Synonyms
  • SF3B14; splicing factor 3B, 14 kDa subunit; pre-mRNA branch site protein p14; SF3b 14 kDa subunit; spliceosome-associated protein, 14 kDa subunit; P14; Ht006; SAP14; CGI-110; HSPC175; SF3B14a
Cat.#:SF3B14-3411HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SF3B14, His-tagged
+Inquiry
Cat.#:SF3B14-4169RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SF3B14 Protein, His-tagged
+Inquiry
Cat.#:SF3B14-1918HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SF3B14 293 Cell Lysate
+Inquiry

Involved Pathway

SF3B14 involved in several pathways and played different roles in them. We selected most pathways SF3B14 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with SF3B14 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Spliceosome
SRSF5B; USP39; SRSF9; SNRPB; SART1; BUD31; SFRS3B; SNRPA; HNRNPA1; CTNNBL1

Protein Function

SF3B14 has several biochemical functions, for example, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SF3B14 itself. We selected most functions SF3B14 had, and list some proteins which have the same functions with SF3B14. You can find most of the proteins on our site.
Function
Related Protein
Function nucleotide binding
Related Protein ZFML; LARP6; ACVR2AA; PKN1B; CPSF6; VSIG8B; RHOGB; RTCB; CELF4; GLULB
Function poly(A) RNA binding
Related Protein ERI3; PTRH1; RBMS2; EIF3L; RIMS1; RPS27L; C4BPA; TRMT2A; NOP56; C14orf21

SF3B14 Related Articles

Paun, BC; Kukuruga, D; et al. Relation Between Normal Rectal Methylation, Smoking Status, and the Presence or Absence of Colorectal Adenomas. CANCER 116:4495-4501(2010).