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SH3GL3

Official Full Name

SH3-domain GRB2-like 3
Overview

Endophilin-A3 is a protein that in humans is encoded by the SH3GL3 gene.
Synonyms

SH3GL3; SH3-domain GRB2-like 3; endophilin-A3; CNSA3; EEN B2; HsT19371; SH3D2C; SH3P13; EEN 2B L3; EEN2BL3; EENB2; Endophilin 3; Endophilin A3; H.sapiens mRNA for protein containing SH3 domain, SH3GL3; SH3 domain containing GRB2 like protein 3; SH3 domain GRB2 like 3; SH3 domain protein 2C; endophilin-3; SH3 domain-containing GRB2-like protein 3; EEN-B2; EEN-2B-L3;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SH3GL3-1599HCL	Recombinant Human SH3GL3 cell lysate		N/A	Inquiry
Human	SH3GL3-4768H	Recombinant Human SH3GL3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	Sh3gl3-5846M	Recombinant Mouse Sh3gl3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Chicken	SH3GL3-6097C	Recombinant Chicken SH3GL3	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
SH3GL3 Related Articles

SH3GL3 involved in several pathways and played different roles in them. We selected most pathways SH3GL3 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SH3GL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Endocytosis	GIT2;SNX32;RABEP1;FGFR2;TSG101;ERBB3A;AGAP2;CHMP4A;RAB11B

SH3GL3 has several biochemical functions, for example, identical protein binding, lipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SH3GL3 itself. We selected most functions SH3GL3 had, and list some proteins which have the same functions with SH3GL3. You can find most of the proteins on our site.

Function	Related Protein
identical protein binding	HSD17B10;PSMD4;GOT2A;DIAP1;KRTAP10-5;ACTN2;PRDX1;BNIP3;S100B
lipid binding	CLINT1;PACSIN3;FABP6;HDLBP;SH3GL3;BPIFB4;PITPNB;PCYT1A;EPN1
protein binding	SNRPB;TFAM;NUP62CL;MSI2;BNIPL;TRIM35;PPP1CC;CDKL3;MAPRE2

SH3GL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SH3GL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SH3GL3.

ATXN2; HTT

Davranche, A; Aviolat, H; et al. Huntingtin affinity for partners is not changed by polyglutamine length: aggregation itself triggers aberrant interactions. HUMAN MOLECULAR GENETICS 20:2795-2806(2011).

Sittler, A; Walter, S; et al. SH3GL3 associates with the huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates. MOLECULAR CELL 2:427-436(1998).