SHC1 Protein, SHC1 SHC (Src homology 2 domain containing) transforming protein 1


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Official Full Name SHC1 SHC (Src homology 2 domain containing) transforming protein 1
Synonyms SHC1; SHC (Src homology 2 domain containing) transforming protein 1; SHC, SHC (Src homology 2 domain containing) transforming protein 1; SHC-transforming protein 1; p66; SH2 domain protein C1; SHC-transforming protein 3; SHC-transforming protein A; SHC (Src homology 2 domain-containing) transforming protein 1; SHC; SHCA; FLJ26504;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SHC1-1862HCL Recombinant Human SHC1 293 Cell Lysate HEK293 N/A
    Human SHC1-2654H Recombinant Human SHC1, GST-tagged E.coli GST
    Human SHC1-30065TH Recombinant Human SHC1, His-tagged E.coli His
    Human SHC1-3579H Recombinant Human SHC1, His-tagged E.coli His
    Mouse SHC1-15090M Recombinant Mouse SHC1 Protein Mammalian Cell His
    Rhesus Macaque SHC1-4192R Recombinant Rhesus monkey SHC1 Protein, His-tagged Mammalian Cell His
    Chicken SHC1-5568C Recombinant Chicken SHC1 Mammalian Cell His

    SHC1 involved in several pathways and played different roles in them. We selected most pathways SHC1 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway RAF1A; CDKN1BB; STAT5A; NCK2B; PIK3R3A; ARAF; PAK7; BADB; HRASA; MAP2K4
    Ras signaling pathway PDGFB; FGF19; NF1; RELA; GNB2; KIT; ZAP70; INSR; GNG11; PLA2G6
    Chemokine signaling pathway CCL2; ARRB1; ELMO1; GM13304; PIK3R1; GNB4; CXCL13; GNG13; SOS1; ROCK1
    Phospholipase D signaling pathway AGPAT3; AGPAT4; MTOR; GRM6; LPAR6; GRB2; PDGFRA; RALGDS; RRAS; RHOA
    Focal adhesion HRAS; SHC3; ITGB5; PAK3; VTN; AKT3A; ITGB7; COL6A5; HRASA; PIK3R1
    Natural killer cell mediated cytotoxicity ULBP3; HRAS; MICB; H60a; SHC1; PPP3CB; LCK; ICAM1; IFNGR1; PPP3CC
    Neurotrophin signaling pathway ARHGDIG; RPS6KA1; GSK3B; NTF3; ABL1; MAPK8; RHOA; PIK3R1; PLCG2; MAP3K3
    Insulin signaling pathway PYGMA; MAP2K2; PRKAR2B; PPP1R3A; HK3; GRB2; CALML3; PDE3B; MTOR; ELK1
    Estrogen signaling pathway KCNJ9; HRAS; GRM1; OPRM1; MAP2K2; GNAQ; ATF6B; AKT2; SOS1; CREB3L1
    Prolactin signaling pathway STAT3; NEK3; PIK3R1; STAT1; FOXO3; HRAS; SHC1; SHC2; SHC3; SHC4
    Bacterial invasion of epithelial cells VCL; ARPC3; RAC1; WASL; CTNNA1; ACTB; DNM3; PIK3R3; PIK3CG; MAD2L2
    MicroRNAs in cancer TNR; TNXB; SHC1; ST14; BMPR2; TP63; PLCG1; IRS1; RASSF1; GLS
    Glioma Pdgfa&Pdgfb; CAMK2D; PDGFRA; MAP2K1; BRAF; PTEN; AKT1; PLCG2; CALML3; TP53
    Chronic myeloid leukemia RB1; PIK3CB; AKT1; RELA; SOS1; PIK3CA; MECOM; GRB2; CRKL; CBLB

    SHC1 has several biochemical functions, for example, ephrin receptor binding, epidermal growth factor receptor binding, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC1 itself. We selected most functions SHC1 had, and list some proteins which have the same functions with SHC1. You can find most of the proteins on our site.

    Function Related Protein
    ephrin receptor binding EFNA5B; CHN1; EFNA2A; EFNA2; FYN; NTRK3; EFNA1; EFNA1B; SHC1; EFNB3
    epidermal growth factor receptor binding SNX2; FAM83B; VAV3; ERBB4; ARF4; HBEGFB; Fert2; PLSCR1; AGR2; GRB2
    insulin receptor binding PTPN1; DOK1; FRS3; INS; DOK2; IGF1R; PHIP; IRS4; DOK3; SNX4
    insulin-like growth factor receptor binding INSR; IGF2; YWHAG; SOCS2; IGF2A; SOCS1; ARRB1; SHC1; PIK3R1; INS
    neurotrophin TRKA receptor binding PLCG1; NGFR; FRS2; GRB2; PIK3R1; SHC1; EFNA5
    phospholipid binding APOB; HIP1RB; ANXA9; ESYT1; CPS1; APOM; PSD2; BAIAP2L2; LRBA; WDFY4
    phosphotyrosine binding GRB2; SHC1; MAPK3; FGR; CBL; LDLRAP1; STAP1; CBLB; MAPK1; PTPN3
    protein binding PPP1CB; ATG101; COA5; MLF1; MAP1LC3B; GNAI2; MAP2K2; CD58; UBC; FOXD3
    protein kinase binding ACVRL1; JAK2; TRPV4; CLTC; TRAF4; TEX14; CCNL1B; CD226; THY1; TRIM5
    protein phosphatase 2A binding MAPT; ANKLE2; HMGCR; CPD; PPP2R4; SMG7; TRP53; ARPP19; SMG5; GRIN3A
    protein tyrosine kinase activity ROS1; MUSK; ERBB4; PTK2BB; EGFR; MET; JAK2; AXL; PTK6B; EPHA4A
    transmembrane receptor protein tyrosine kinase adaptor activity SHC1; GAB2; FRS2; TRAT1; BLNK; SH2B2; STAP1; IRS1; PIK3R1; DOK2

    SHC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC1.


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