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SHC1

  • Official Full Name

    SHC1 SHC (Src homology 2 domain containing) transforming protein 1

  • Synonyms

    SHC1; SHC (Src homology 2 domain containing) transforming protein 1; SHC, SHC (Src homology 2 domain containing) transforming protein 1; SHC-transforming protein 1; p66; SH2 domain protein C1; SHC-transforming protein 3; SHC-transforming protein A; SHC (Src homology 2 domain-containing) transforming protein 1; SHC; SHCA; FLJ26504;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SHC1-3579H Recombinant Human SHC1, His-tagged E.coli His
Human SHC1-2654H Recombinant Human SHC1, GST-tagged E.coli GST 1-169AA
Human SHC1-30065TH Recombinant Human SHC1, His-tagged E.coli His 474 amino acids
Human SHC1-1862HCL Recombinant Human SHC1 293 Cell Lysate HEK293 N/A
Human SHC1-1005H Recombinant Human SHC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SHC1-6283H Recombinant Human SHC1 Protein (Glu272-His559), N-His tagged E.coli N-His Glu272-His559
Mouse SHC1-15090M Recombinant Mouse SHC1 Protein Mammalian Cell His
Mouse Shc1-5854M Recombinant Mouse Shc1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SHC1-8141M Recombinant Mouse SHC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SHC1-8141M-B Recombinant Mouse SHC1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SHC1-4192R Recombinant Rhesus monkey SHC1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SHC1-4008R Recombinant Rhesus Macaque SHC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SHC1-4008R-B Recombinant Rhesus Macaque SHC1 Protein Pre-coupled Magnetic Beads HEK293
Chicken SHC1-5568C Recombinant Chicken SHC1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SHC1 Related Research Area
  • SHC1 Related Signal Pathway

SHC1 involved in several pathways and played different roles in them. We selected most pathways SHC1 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ErbB signaling pathwayPRKCA;PLCG2;MYCB;CBLB;MAPK10;PIK3R3;GAB1;PAK2A;BAD
Ras signaling pathwayAKT1;RASA4;PDGFB;IGF1R;FGF6;IGF1;IKBKG;INS1;PLA2G3
Chemokine signaling pathwayPRKCD;GNG8;LYN;GNGT2;CCL16;FGR;CCR10;CCL8;SOS1
Phospholipase D signaling pathwayPDGFD;MAPK3;FCER1G;RALB;PIK3R3;SPHK1;GRM3;SYK;LPAR3
Focal adhesionRAF1;MYL2;LAMC2;PAK6;MLCK2;PIK3R3B;RHOAB;ITGB8;VASPA
Natural killer cell mediated cytotoxicityKIR2DS2;ULBP2;KIR2DS4;PRKCB;SH2D1A;IFNA8;HLA-E;IFNA17;SH3BP2
Neurotrophin signaling pathwayRELA;IKBKB;ARHGDIA;SH2B3;PTPN11;CAMK4;GRB2;BCL2;PRDM4
Insulin signaling pathwayFOXO1;PYGB;NRAS;PPP1R3DA;SREBF1;PRKACAB;PRKAR1A;RHOQ;PPP1R3A
Estrogen signaling pathwayCALML3;CALM3;Adcy4;KCNJ3;SHC2;CREB3L1;GNAS;ESR1;KCNJ6
Prolactin signaling pathwayINS;LHCGR;SOCS4;PIK3CG;PIK3R3;NRAS;SOCS1;PRP2;MAP2K2
AlcoholismMAOB;HIST3H3;HIST2H2BB;HIST1H2BC;H2AFB2;HIST2H4;HIST1H2AG;HRAS;CREB3L2
Bacterial invasion of epithelial cellsARPC1A;SEPT6;CTNNA2;SHC1;PTK2;CAV1;ELMO3;ELMO1;PIK3R2
MicroRNAs in cancerBCL2;RPTOR;RDX;SPRY2;EZH2;VIM;ZFPM2;SIRT1;FSCN1
GliomaTRP53;MAP2K2;PIK3CA;AKT1;PIK3R1;CAMK2G;CALML3;SHC2;PDGFB
Chronic myeloid leukemiaTGFB3;CBL;SHC4;TGFB1;NFKB1;SHC3;TGFBR1;ARAF;ABL1

SHC1 has several biochemical functions, for example, ephrin receptor binding, epidermal growth factor receptor binding, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC1 itself. We selected most functions SHC1 had, and list some proteins which have the same functions with SHC1. You can find most of the proteins on our site.

Function Related Protein
ephrin receptor bindingEFNB2B;GRB2;SHC1;EFNA2A;SRC;EFNA5;EFNA4;PTPN1;CBL
epidermal growth factor receptor bindingSHC1;EGF;ARF4;LINGO1;EFEMP1;VAV3;VAV2;LINGO1B;HBEGFA
insulin receptor bindingFRS3;DOK2;FRS2B;FRS2;IRS1;IRS2;IGF1R;SLC2A2;DOK1B
insulin-like growth factor receptor bindingSOCS1;SOCS2;YWHAG;ARRB1;IGF2B;INS;YWHAH;IGF2A;INS2
neurotrophin TRKA receptor bindingGRB2;SHC1;FRS2;EFNA5;PLCG1;PIK3R1;NGFR
phospholipid bindingAPOA1;SPTB;GOT2;GLTPD1;NOXO1;PRKCI;APOE;WDFY4;APOH
phosphotyrosine bindingCBLB;PTPN3;CBLC;STAP1;MAPK3;MAPK1;ACP2;GRB2;ZAP70
protein bindingSOX4;CAMKK1;CCL18;HSPA1L;GTF2H1;INPPL1;DNAJB9;AP1M2;SKIL
protein kinase bindingGRB7;FGR;PPP1CB;CCNB1;CACNB2;MS4A2;LIPE;TCTN2;ADIPOR1
protein phosphatase 2A bindingIGBP1;PPP2R4;BCL2;TP53;FOXO1;STRN4;TRP53;GRIN3A;CTTNBP2NL
protein tyrosine kinase activityAXL;FGFR4;FGFR3;DYRK3;IGF1RA;ERBB3A;LYN;SHC1;DSTYK
transmembrane receptor protein tyrosine kinase adaptor activityIRS1;DOK2;PIK3R1;BLNK;SH2B2;STAP1;SHC1;FRS2;TRAT1

SHC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC1.

GRB2

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