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SIM1

  • Official Full Name

    single-minded homolog 1

  • Overview

    Single-minded homolog 1 also known as class E basic helix-loop-helix protein 14 (bHLHe14) is a protein that in humans is encoded by the SIM1 gene.
  • Synonyms

    SIM1; single-minded homolog 1 (Drosophila); single minded (Drosophila) homolog 1; single-minded homolog 1; bHLHe14; class E basic helix-loop-helix protein 14;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse SIM1-15139M Recombinant Mouse SIM1 Protein Mammalian Cell His
Mouse SIM1-8175M-B Recombinant Mouse SIM1 Protein Pre-coupled Magnetic Beads HEK293
Mouse SIM1-8175M Recombinant Mouse SIM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SIM1 Related Articles

SIM1 involved in several pathways and played different roles in them. We selected most pathways SIM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SIM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

SIM1 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIM1 itself. We selected most functions SIM1 had, and list some proteins which have the same functions with SIM1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingABI2;CROP;SURF6;TTC5;CENPA;LIG1;HIST2H2L;DNTT;H2AFVA
RNA polymerase II transcription factor activity, sequence-specific DNA bindingATF4B2;TFDP1A;FOXJ1A;PAX6;MEF2A;PLAGL1;ELF2;SOX8B;OVOL3
protein bindingS1PR3;NEK2;AQP1;PSMA4;KIAA0408;PPCDC;PSME3;CRY1A;CTSH
protein dimerization activityGRIN2A;SCXB;NPAS2;PRDX5;ARNTL1A;STX2;AHRR;ASCL1A;GGN
protein heterodimerization activityH2AFV;SPTAN1;NR2C2;ARNT;SMAD3;HIST1H2BF;Defa-rs7;FLOT2;TTR
transcription factor activity, sequence-specific DNA bindingZNF726;CNBP;ZSCAN4D;FOXK2;HIF1AB;ZIC3;RORA;DMRT1;BACH1A

SIM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIM1.

Arnt; Hsp90aa1; Ilk

Coumailleau, P; Duprez, D; et al. Sim1 and Sim2 expression during chick and mouse limb development. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 53:149-157(2009).
Zhao, XF; Xu, NY; et al. Single-minded 1 gene mapping and its variants association with growth, carcass composition and meat quality traits in the pig. ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 21:941-946(2008).
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