sim1
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  • Official Full Name
  • single-minded homolog 1
  • Background
  • Single-minded homolog 1 also known as class E basic helix-loop-helix protein 14 (bHLHe14) is a protein that in humans is encoded by the SIM1 gene.
  • Synonyms
  • SIM1; single-minded homolog 1 (Drosophila); single minded (Drosophila) homolog 1; single-minded homolog 1; bHLHe14; class E basic helix-loop-helix protein 14
Cat.#:SIM1-15139MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SIM1 Protein
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Protein Function

SIM1 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIM1 itself. We selected most functions SIM1 had, and list some proteins which have the same functions with SIM1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein IRX3A; ATM; RFX8; TA; FOXB1B; CALR; FOXJ1; ZNF18; TNP1; KDM5A
Function RNA polymerase II transcription factor activity, sequence-specific DNA binding
Related Protein TRP53; TFDP1; EPAS1; TFAP2B; FOXA; SPIC; SOX21; MKX; ELK4; FOXS1
Function protein binding
Related Protein IL18; STX12; TNFRSF10A; TBC1D7; NME7; PDP1; PSMB8; E4F1; NDRG1; BAZ2B
Function protein dimerization activity
Related Protein CLOCKA; MYCLB; NPAS2; HNF1A; EBF3A; PDCD6; MEF2D; ID4; MYCH; SCXB
Function protein heterodimerization activity
Related Protein KCNK9; HIST1H4G; LIFR; TIMELESS; CYBB; MYOD1; CHRNA5; ZHX1; UGT1A4; PDZD7
Function transcription factor activity, sequence-specific DNA binding
Related Protein CARF; ZKSCAN6; IRF2A; BACH1; ATF3; SLC30A9; HSFY1; NANOG; ESR2A; ZNF643

Interacting Protein

SIM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIM1.
Arnt; Hsp90aa1; Ilk

SIM1 Related Articles

Coumailleau, P; Duprez, D; et al. Sim1 and Sim2 expression during chick and mouse limb development. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 53:149-157(2009).
Zhao, XF; Xu, NY; et al. Single-minded 1 gene mapping and its variants association with growth, carcass composition and meat quality traits in the pig. ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES 21:941-946(2008).