six3
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  • Official Full Name
  • SIX homeobox 3
  • Background
  • This gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2.
  • Synonyms
  • SIX3; SIX homeobox 3; holoprosencephaly 2, alobar or semilobar , HPE2, sine oculis homeobox homolog 3 (Drosophila); homeobox protein SIX3; Sine oculis homeobox homolog 3; SIX3_HUMAN; OTTHUMP00000201650; HPE2
Cat.#:SIX3-15163MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SIX3 Protein
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Cat.#:SIX3-5935CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SIX3
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Cat.#:SIX3-1823HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SIX3 293 Cell Lysate
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Protein Function

SIX3 has several biochemical functions, for example, RNA polymerase II distal enhancer sequence-specific DNA binding, histone deacetylase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIX3 itself. We selected most functions SIX3 had, and list some proteins which have the same functions with SIX3. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II distal enhancer sequence-specific DNA binding
Related Protein ARID3B; GATA2; MED12; HNRNPC; REL; H3F3B; RELA; PBX3; MEOX2; SFPQ
Function histone deacetylase binding
Related Protein CRY1; SFPQ; NKX2-5; YY1; NCOR2; ZFP932; GLI3; NUDT21; MAPK8; HIST1H1B
Function protein binding
Related Protein CGGBP1; FLI1; TAPBP; FRS2; AIMP1; CDON; SMCO4; SLC41A3; CCDC112; RPIA
Function transcription coactivator activity
Related Protein TCERG1; NFATC4; ZSCAN1; RNF14; MLL5; MMS19; PER2; ATXN7L3; NCOA3; HCFC1
Function transcription corepressor binding
Related Protein FAM89B; RORA; NR1D1; SIX3; HDGF
Function transcription factor activity, sequence-specific DNA binding
Related Protein RXRAA; NKX2; ZNF624; TAL1; RORC; TRPS1; TRIM25; ZIK1; TSC22D1; FOXS1
Function transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein MEOX2; SPI1; ARID3B; NFE2L2; PBX3; HCFC1; CUX1; REL; PROP1; FOXH1