slc1a5
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  • Official Full Name
  • solute carrier family 1 (neutral amino acid transporter), member 5
  • Background
  • The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011]
  • Synonyms
  • SLC1A5; solute carrier family 1 (neutral amino acid transporter), member 5; R16; AAAT; ATBO; M7V1; RDRC; ASCT2; M7VS1; neutral amino acid transporter B(0); ATB(0); RD114 virus receptor; baboon M7 virus receptor; neutral amino acid transporter B; solute carrier family 1 member 5; RD114/simian type D retrovirus receptor; sodium-dependent neutral amino acid transporter type 2;
Cat.#:RDRC-2241HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RDRC protein, GST-tagged
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Cat.#:SLC1A5-1195HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SLC1A5 protein, His & GST-tagged
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Cat.#:SLC1A5-922CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus SLC1A5 Protein, His-tagged
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Cat.#:SLC1A5-7769ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SLC1A5
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Involved Pathway

SLC1A5 involved in several pathways and played different roles in them. We selected most pathways SLC1A5 participated on our site, such as Protein digestion and absorption, Central carbon metabolism in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC1A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Protein digestion and absorption
CPB1; PRSS3; ELN; COL6A5; COL13A1; SLC8A1; COL10A1; ATP1B1; KCNK5; MME
Central carbon metabolism in cancer
MAP2K1; HK2; RAF1; PIK3CA; SIRT3; FGFR1; HIF1A; PIK3CD; NTRK3; PDHB

Protein Function

SLC1A5 has several biochemical functions, for example, L-glutamine transmembrane transporter activity, neutral amino acid transmembrane transporter activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC1A5 itself. We selected most functions SLC1A5 had, and list some proteins which have the same functions with SLC1A5. You can find most of the proteins on our site.
Function
Related Protein
Function L-glutamine transmembrane transporter activity
Related Protein SLC38A1; SLC1A5; SLC1A4; SLC38A7; SLC38A3
Function neutral amino acid transmembrane transporter activity
Related Protein SLC3A2; SLC7A10; SLC43A2B; SLC43A1B; SLC15A1B; SLC1A5; SLC43A2; SLC6A19A; SLC43A2A; SLC6A19B
Function protein binding
Related Protein TFAM; PSMD2; DR1; ARGLU1; FAM164C; NRP1B; LUZP4; LRRC33; KRT79; MCM5
Function receptor activity
Related Protein ANTXRL; PAQR5; SMAGP; NPR2; TNFRSF11A; HTR3A; ITGB3A; CD244; PLXNA1; CALCR
Function sodium:dicarboxylate symporter activity
Related Protein SLC1A4; SLC13A5A; SLC1A7A; SLC1A3A; SLC1A2A; SLC13A3; SLC1A5; SLC1A1; SLC1A2B; SLC1A3B
Function virus receptor activity
Related Protein SLC52A2; PVRL2; CLEC5A; CD209; CXCR4; SLAMF1; DAG1; F11R; MOG; ITGB3

Interacting Protein

SLC1A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC1A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC1A5.
RNF5; bnps-skatole; ganglioside_gm1; 4504987; MPDU1; USP19; TNFRSF1A; TNFRSF1B; HLA-B; MAP3K1; USP50; NEK6; GSTK1; TBC1D17; 15-deoxy-delta(12,14

SLC1A5 Related Articles

Indo, Y; Takeshita, S; et al. Metabolic Regulation of Osteoclast Differentiation and Function. JOURNAL OF BONE AND MINERAL RESEARCH 28:2392-2399(2013).
Metzler, R; Meleshkevitch, EA; et al. An SLC6 transporter of the novel B-0,B-- system aids in absorption and detection of nutrient amino acids in Caenorhabditis elegans. JOURNAL OF EXPERIMENTAL BIOLOGY 216:2843-2857(2013).