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Official Full Name solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
Background This gene is a member of the mitochondrial carrier family. The encoded protein transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. The protein is an essential component of the urea cycle, and functions in ammonium detoxification and biosynthesis of the amino acid arginine. Mutations in this gene result in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. There is a pseudogene of this locus on the Y chromosome.
Synonyms SLC25A15; solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15; HHH, ORNT1; mitochondrial ornithine transporter 1; D13S327; ORC1; ornithine transporter 1; ORNT1; Solute carrier family 25 member 15; HHH; Ornithine transporter, mitochondrial; ORNT1_HUMAN
    • Species :
    • Chicken
    • Human
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SLC25A15-2717H Recombinant Human SLC25A15, His-tagged E.coli His
    Human SLC25A15-2990H Recombinant Human Solute Carrier Family 25 (Mitochondrial Carrier; Ornithine Transporter) Member 15, T7-tagged E.coli T7
    Human SLC25A15-31413TH Recombinant Human SLC25A15, T7 -tagged E.coli T7
    Chicken SLC25A15-1824C Recombinant Chicken SLC25A15 Mammalian Cell His

    SLC25A15 involved in several pathways and played different roles in them. We selected most pathways SLC25A15 participated on our site, such as Metabolism, Metabolism of amino acids and derivatives, Metabolism of polyamines, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism MED23; AQP1A.2; MED20; ACOT2; CPTP; CERS4A; PDK4; NUDT3B; B3GNT3; APOEA
    Metabolism of amino acids and derivatives CKMT1B; FTCD; TPH2; AZIN1B; SLC6A12; OAZ1; CKMT2A; DCT; AFMID; ALDH9A1A.2
    Metabolism of polyamines PAOX; AZIN1A; SLC6A12; OAZ2B; CKMB; NQO1; CKMT2A; SLC6A7; SLC25A2; CKMT2
    Urea cycle SLC25A15A; SLC25A2; NAGS; SLC25A15B; SLC25A15

    SLC25A15 has several biochemical functions, for example, L-ornithine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A15 itself. We selected most functions SLC25A15 had, and list some proteins which have the same functions with SLC25A15. You can find most of the proteins on our site.

    Function Related Protein
    L-ornithine transmembrane transporter activity SLC7A1; SLC25A15; SLC7A4; SLC7A3A; SLC7A3

    SLC25A15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A15 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A15.

    Martinelli, D; Diodato, D; et al. The hyperornithinemia-hyperammonemia-homocitrullinuria syndrome. ORPHANET JOURNAL OF RARE DISEASES 10:-(2015).
    Tunali, NE; Marobbio, CMT; et al. A novel mutation in the SLC25A15 gene in a Turkish patient with HHH syndrome: Functional analysis of the mutant protein. MOLECULAR GENETICS AND METABOLISM 112:25-29(2014).

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