• Official Full Name
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
  • Background
  • The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.
  • Synonyms
  • SMARCAL1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; ATP driven annealing helicase; HARP; HepA related protein; HHARP; SMARCA like Protein 1; Sucrose nonfermenting protein 2 like 1; SWI/SNF Related; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A like protein 1; HepA-related protein; SMARCA-like protein 1; ATP-driven annealing helicase; sucrose nonfermenting protein 2-like 1
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human SMARCAL1 Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SMARCAL1 Protein, His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SMARCAL1, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SMARCAL1 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SMARCAL1 Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SMARCAL1
Source (Host):Species:Human
Product nameRecombinant Human SMARCAL1 cell lysate

Protein Function

SMARCAL1 has several biochemical functions, for example, ATP binding, DNA-dependent ATPase activity, annealing helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCAL1 itself. We selected most functions SMARCAL1 had, and list some proteins which have the same functions with SMARCAL1. You can find most of the proteins on our site.
Related Protein
Function ATP binding
Related Protein PAK7; RPS6KAL; STK31; MYLK; STK32C; DNAH14; FYN; NEK6; DCLK1A; ARAF
Function DNA-dependent ATPase activity
Related Protein RAD51B; ERCC2; DDX11; RAD51L3; MSH2; DHX36; CHD6; MSH3; SMARCA4; MSH5
Function annealing helicase activity
Function helicase activity
Related Protein GTF2F2A; DDX3; SMARCA4; DHX37; DDX58; DHX36; ACTG2; PL10; EIF4A1B; DDX19
Function protein binding
Related Protein ZNF707; SEMA4D; TCEB2; KRT25; FBLIM1; ECHS1; GADD45B; GPANK1; C1GALT1C1; RNF32

Interacting Protein

SMARCAL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCAL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCAL1.
RPA2; NS1; ssdna_dt