smarcd1
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  • Official Full Name
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
  • Background
  • The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • SMARCD1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1; BAF60A; CRACD1; Rsc6p; Swp73-like protein; BRG1-asso
Cat.#:SMARCD1-15604MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SMARCD1 Protein
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Cat.#:SMARCD1-9819ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SMARCD1
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Cat.#:SMARCD1-1668HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SMARCD1 293 Cell Lysate
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Involved Pathway

SMARCD1 involved in several pathways and played different roles in them. We selected most pathways SMARCD1 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, Glucocorticoid receptor regulatory network, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMARCD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chromatin modifying enzymes
MSL3; DR1; WDR77; MSL2; ARID4A; DPY30; COPRS; NCOA2; RUVBL2; MSL2B
Chromatin organization
PRMT5; SAP30L; CHD4; PHF20B; SUZ12A; MBD3A; KAT6A; ARID5B; CCDC101; KAT7B
Glucocorticoid receptor regulatory network
KRT14; KRT5; NR1I3; SMARCD1; SMARCA4; BGLAP; CSN2; KRT17; EGR1; SMARCC2
Prostate Cancer
TRP53; BRAF; SRD5A2; BAD; PDGFRB; PIK3R1; NFKBIA; PIK3CB; ERBB2; PIK3R2
RMTs methylate histone arginines
PRMT6; SMARCD3; SMARCC1B; PBRM1L; COPRS; SMARCB1B; PBRM1; PRMT5; SMARCA2; SMARCB1A

Protein Function

SMARCD1 has several biochemical functions, for example, chromatin binding, protein binding, protein complex scaffold. Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCD1 itself. We selected most functions SMARCD1 had, and list some proteins which have the same functions with SMARCD1. You can find most of the proteins on our site.
Function
Related Protein
Function chromatin binding
Related Protein SHMT2; STAT5B; HOXD13; ARID3C; SP3; ISL1; TADA2B; HMGN5; LMO2; FOXC1A
Function protein binding
Related Protein PAX6; MALSU1; APITD1; RAB9A; BATF; PELI3; NELL2; PROC; NHP2L1; SNRPN
Function protein complex scaffold
Related Protein PKP2; GNB2L1; MAGI1B; MAGI1; MAP2K2; AKAP13; KLHL17; SLC9A1; ARRB2; SEPT2
Function receptor binding
Related Protein AGRP; FGF10A; NRG2B; CD72; TENM2; ACOT8; ITGA1; MLN; MTSS1; CCL13
Function transcription coactivator activity
Related Protein PRPF6; RBPMS; SMARCB1; MCIN; MED1; TADA2A; SOX10; CITED4; BRCA1; CTNNB1

Interacting Protein

SMARCD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCD1.
SMARCC1; SMARCA4; VPS37B; MED4; CALCOCO2