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SMARCD2

  • Official Full Name

    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2

  • Overview

    The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    SMARCD2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2; BAF60B; chromatin remodeling complex BAF60B subunit;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Rat SMARCD2-5614R Recombinant Rat SMARCD2 Protein Mammalian Cell His
Rat SMARCD2-5273R Recombinant Rat SMARCD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SMARCD2-5273R-B Recombinant Rat SMARCD2 Protein Pre-coupled Magnetic Beads HEK293
  • SMARCD2 Related Articles
  • SMARCD2 Related Research Area

SMARCD2 involved in several pathways and played different roles in them. We selected most pathways SMARCD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SMARCD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

SMARCD2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCD2 itself. We selected most functions SMARCD2 had, and list some proteins which have the same functions with SMARCD2. You can find most of the proteins on our site.

Function Related Protein

SMARCD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCD2.

Kurihara, M; Kimura, AP; et al. Characterization of the human TCAM1P pseudogene and its activation by a potential dual promoter-enhancer: Comparison with a protein-coding mouse orthologue. FEBS LETTERS 589:540-547(2015).
Gong, JH; Zhu, M; et al. Genetic variants in SMARC genes are associated with DNA damage levels in Chinese population. TOXICOLOGY LETTERS 229:327-332(2014).
  • Q&As
  • Reviews

Q&As (5)

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How does SMARCD2 contribute to drug resistance in certain cancers? 02/04/2023

Elevated SMARCD2 expression has been linked to drug resistance in some cancers, impacting the efficacy of certain anticancer drugs.

Are there any associations between SMARCD2 expression and patient survival rates in specific cancers? 08/12/2021

Some studies suggest that high SMARCD2 expression is associated with poor prognosis in certain cancers, impacting patient survival rates.

How does SMARCD2 influence the epithelial-mesenchymal transition (EMT) in cancer cells? 07/28/2021

SMARCD2 has been shown to regulate EMT, a process crucial for cancer metastasis, making it a potential therapeutic target.

Are there any ongoing clinical trials targeting SMARCD2 in cancer patients? 01/15/2021

It is advisable to check clinical trial databases for the latest information, but as of my last update in 2022, there might be trials investigating SMARCD2-related therapies.

In what ways does SMARCD2 interact with other proteins or pathways in cancer cells? 10/14/2020

SMARCD2 interacts with various proteins and pathways, influencing cellular processes like cell cycle regulation and DNA repair in cancer cells.

Customer Reviews (3)

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Reviews
09/22/2022

    the manufacturer of SMARCD2 provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.

    03/09/2021

      The outstanding level of customer service adds extra reassurance and confidence in using the SMARCD2 protein for my scientific investigations.

      07/07/2016

        The SMARCD2 protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.

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