smpd2
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  • Official Full Name
  • sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
  • Background
  • Sphingomyelinases (SMases) catalyze the hydrolysis of sphingomyelin to produce ceramide and phosphocholine. Ceramide is an important bioactive lipid triggering signal transduction involved in cell proliferation, apoptosis and differentiation. A number of
  • Synonyms
  • SMPD2; sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase); sphingomyelin phosphodiesterase 2; ISC1; nSMase; N-SMase; lyso-PAF-PLC; neutral sphingomyelinase; lyso-platelet-activating factor-phospholipase C; NSMASE1
Cat.#:SMPD2-29731THTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human SMPD2 Protein, GST-tagged
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Cat.#:SMPD2-8253HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SMPD2 protein, His & GST-tagged
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Cat.#:SMPD2-15640MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SMPD2 Protein
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Cat.#:SMPD2-5624RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SMPD2 Protein
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Cat.#:Smpd2-8254RTag:His|GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Smpd2 protein, His & GST-tagged
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Cat.#:SMPD2-4350RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SMPD2 Protein, His-tagged
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Cat.#:SMPD2-614HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human SMPD2 lysate
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Involved Pathway

SMPD2 involved in several pathways and played different roles in them. We selected most pathways SMPD2 participated on our site, such as Sphingolipid metabolism, Metabolic pathways, Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMPD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Sphingolipid metabolism
NEU3.2; PPM1LA; SUMF2; SMPD4; PPAP2D; CERS2A; SPHK2; R05D11.9; SGPP2; SMPD2
Metabolic pathways
ATP6V1E1; RDH11; COMTB; INPP1; PKLR; GBA; PIGA; LPIN3; DPM1; PAICS
Sphingolipid signaling pathway
CERS2; PIK3CG; PPP2R5B; GNAI3; MAP2K1; GNA12; KRAS; PTEN; PRKCA; ASAH1

Protein Function

SMPD2 has several biochemical functions, for example, metal ion binding, sphingomyelin phosphodiesterase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SMPD2 itself. We selected most functions SMPD2 had, and list some proteins which have the same functions with SMPD2. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein ZBTB6; ZDHHC20A; RAB11FIP3; NRXN1; CYB561D2; FGD4; FGD4A; ZBTB7A; FDX1B; IMPDH2
Function sphingomyelin phosphodiesterase activity
Related Protein SMPD3; ENPP7; SMPDL3B; SMPD4; SMPD2; SMPD1; SMPDL3A; SMPD5; SMPD2A