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SNRNP35

  • Official Full Name

    small nuclear ribonucleoprotein 35kDa (U11/U12)

  • Overview

    The protein encoded by this gene is a homolog of U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal is rich in Arg/Asp and Arg/Glu dipeptides; a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. This gene is differentially expressed in a variety of human tissues. Alternative splicing results in multiple transcript variants encoding distinct proteins.
  • Synonyms

    HM-1; MGC138160; U1SNRNPBP; SNRNP35; U11/U12 small nuclear ribonucleoprotein 35 kDa protein; U11/U12-35K; protein HM-1; U11/U12 snRNP 35K; OTTHUMP00000236244; OTTHUMP00000236245; U11/U12 snRNP 35 kDa protein; U1 snRNP binding protein homolog; U1 snRNP-binding protein homolog; U1-snRNP binding protein homolog;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SNRNP35-2847H Recombinant Human SNRNP35, His-tagged E.coli His 1-246aa
Human SNRNP35-1623HCL Recombinant Human SNRNP35 293 Cell Lysate HEK293 N/A
Human SNRNP35-769HFL Recombinant Full Length Human SNRNP35 Protein, C-Flag-tagged Mammalian cells Flag
Human SNRNP35-2058H Recombinant Human SNRNP35 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SNRNP35-2058H-B Recombinant Human SNRNP35 Protein Pre-coupled Magnetic Beads HEK293
Mouse SNRNP35-15687M Recombinant Mouse SNRNP35 Protein Mammalian Cell His
Mouse SNRNP35-8532M Recombinant Mouse SNRNP35 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Snrnp35-6002M Recombinant Mouse Snrnp35 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SNRNP35-8532M-B Recombinant Mouse SNRNP35 Protein Pre-coupled Magnetic Beads HEK293
Rat SNRNP35-5647R Recombinant Rat SNRNP35 Protein Mammalian Cell His
Rat SNRNP35-5306R Recombinant Rat SNRNP35 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SNRNP35-5306R-B Recombinant Rat SNRNP35 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SNRNP35-3326Z Recombinant Zebrafish SNRNP35 Mammalian Cell His
Chicken SNRNP35-4752C Recombinant Chicken SNRNP35 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SNRNP35 Related Articles

SNRNP35 involved in several pathways and played different roles in them. We selected most pathways SNRNP35 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNRNP35 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionTHG1L;ZNF34;MED8;ZNF180;MTA1;ADAT2;ZNF701;ZKSCAN3;GTF3C3
Processing of Capped Intron-Containing Pre-mRNADNAJC8;PAPOLA;WTAP;NXF1;RNPS1;METTL3;HNRNPL;CCAR1;SF3B2
mRNA SplicingHNRNPR;HNRNPD;SUGP1;HNRNPA0L;CCAR1;PCBP2;PTBP1B;SNRNP25;ZMAT5
mRNA Splicing - Minor PathwayZMAT5;RNPC3;PDCD7;TXNL4A;PRPF8;SF3B4;SNRNP48;SNRNP35;SF3B2

SNRNP35 has several biochemical functions, for example, mRNA binding, nucleotide binding, snRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNRNP35 itself. We selected most functions SNRNP35 had, and list some proteins which have the same functions with SNRNP35. You can find most of the proteins on our site.

Function Related Protein
mRNA bindingCSTF2;EIF4ENIF1;ELAVL1;AGO2;FXR2;SNRPC;SRSF1;TRA2B;CALR
nucleotide bindingRBM24B;SFRS3A;TRA2B;RBM39A;DDX39AA;RAB35B;CHD1L;TUBA8L3;BSK146
snRNA bindingRBPMS;CDK9;HEXIM1;SNRNP35;CCNT1;NCBP2;HEXIM2

SNRNP35 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNRNP35 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNRNP35.

SRPK2; TNFSF11; MAP4K2; ILK; TAB1; PTBP3

Stark, MR; Dunn, EA; et al. Dramatically reduced spliceosome in Cyanidioschyzon merolae. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E1191-E1200(2015).
Ashour, J; Schmidt, FI; et al. Intracellular Expression of Camelid Single-Domain Antibodies Specific for Influenza Virus Nucleoprotein Uncovers Distinct Features of Its Nuclear Localization. JOURNAL OF VIROLOGY 89:2792-2800(2015).
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