snrnp35
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  • Official Full Name
  • small nuclear ribonucleoprotein 35kDa (U11/U12)
  • Background
  • The protein encoded by this gene is a homolog of U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal is rich in Arg/Asp and Arg/Glu dipeptides; a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. This gene is differentially expressed in a variety of human tissues. Alternative splicing results in multiple transcript variants encoding distinct proteins.
  • Synonyms
  • HM-1; MGC138160; U1SNRNPBP; SNRNP35; U11/U12 small nuclear ribonucleoprotein 35 kDa protein; U11/U12-35K; protein HM-1; U11/U12 snRNP 35K; OTTHUMP00000236244; OTTHUMP00000236245; U11/U12 snRNP 35 kDa protein; U1 snRNP binding protein homolog; U1 snRNP-binding protein homolog; U1-snRNP binding protein homolog
Cat.#:SNRNP35-2847HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SNRNP35, His-tagged
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Cat.#:SNRNP35-15687MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SNRNP35 Protein
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Cat.#:SNRNP35-5647RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SNRNP35 Protein
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Cat.#:SNRNP35-4752CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SNRNP35
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Cat.#:SNRNP35-3326ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SNRNP35
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Cat.#:SNRNP35-1623HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SNRNP35 293 Cell Lysate
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Involved Pathway

SNRNP35 involved in several pathways and played different roles in them. We selected most pathways SNRNP35 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNRNP35 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
ZNF446; ZNF324; NR0B2A; C7orf59; ZNF688; ZNF285A; RPP30; TPRKB; PRDM7; ZNF621
Processing of Capped Intron-Containing Pre-mRNA
SNRNP25; PTBP1B; HNRNPD; METTL14; ZMAT5; WTAP; HNRNPH1; NUDT21; BCAS2; HNRNPA0L
mRNA Splicing
HNRNPH1; SF3A1; HNRNPA0L; RNPC3; PTBP1A; HNRNPUL1; CD2BP2; SNRNP35; PCBP2; SF3B2
mRNA Splicing - Minor Pathway
ZCRB1; SF3B4; PDCD7; ZMAT5; PRPF8; SNRNP25; RNPC3; SF3B2; TXNL4A; SNRNP35

Protein Function

SNRNP35 has several biochemical functions, for example, mRNA binding, nucleotide binding, snRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNRNP35 itself. We selected most functions SNRNP35 had, and list some proteins which have the same functions with SNRNP35. You can find most of the proteins on our site.
Function
Related Protein
Function mRNA binding
Related Protein CSTF2; RBM8A; CSTF2T; SLBP; RBFOX1; CCDC55; ADARB1; RBM4; NXF2; ZFP36
Function nucleotide binding
Related Protein TIAL1; RABL2; SSB; TNRC6B; CPSF6; PPIP5K2; DHX36; EPHA2A; PTK2AA; TIA1L
Function snRNA binding
Related Protein CDK9; HEXIM2; RBPMS; NCBP2; CCNT1; HEXIM1; SNRNP35

Interacting Protein

SNRNP35 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNRNP35 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNRNP35.
SRPK2; TNFSF11; MAP4K2; ILK; TAB1; PTBP3

SNRNP35 Related Articles

Stark, MR; Dunn, EA; et al. Dramatically reduced spliceosome in Cyanidioschyzon merolae. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E1191-E1200(2015).
Ashour, J; Schmidt, FI; et al. Intracellular Expression of Camelid Single-Domain Antibodies Specific for Influenza Virus Nucleoprotein Uncovers Distinct Features of Its Nuclear Localization. JOURNAL OF VIROLOGY 89:2792-2800(2015).