Recombinant Full Length Human SNRNP35 Protein, C-Flag-tagged

• Cat.No.: SNRNP35-769HFL
• Product Overview: Recombinant Full Length Human SNRNP35 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a homolog of the U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, which is a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. Alternative splicing results in multiple transcript variants encoding two distinct isoforms and representing a non-protein coding variant.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 29.8 kDa
• AA Sequence: MKPANMNDWMPIAKEYDPLKAGSID GTDEDPHDRAVWRAMLARYVPNKGV IGDPLLTLFVARLNLQTKED KLKEVFSRYGDIRRLRLVRDLVTGF SKGYAFIEYKEERAVIKAYRDADGL VIDQHEIFVDYELERTLKGW IPRRLGGGLGGKKESGQLRFGGRDR PFRKPINLPVVKNDLYREGKRERRE RSRSRERHWDSRTRDRDHDR
  GREKRWQEREPTRVWPDNDWERERD FRDDRIKGREKKERGKTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: SNRNP35 small nuclear ribonucleoprotein U11/U12 subunit 35 [ Homo sapiens (human) ]
• Official Symbol: SNRNP35
• Synonyms: HM1; HM-1; U1SNRNPBP
• Gene ID: 11066
• mRNA Refseq: NM_180699.3
• Protein Refseq: NP_851030.1
• MIM: 619631
• UniProt ID: Q16560