ST13 Protein, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)

ST13

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ST13

Official Full Name suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
Background The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70;and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which;requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated;in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor gene.
Synonyms ST13; suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein); hsc70-interacting protein; FAM10A1; HIP; HSPABP1; P48; progesterone receptor associated p48 protein; SNC6; Hsp70-interacting protein; aging-associated protein 2; putativ
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ST13-1334H Recombinant Human ST13 Protein, MYC/DDK-tagged E.coli Myc/DDK
    Human ST13-1701HCL Recombinant Human ST13 cell lysate N/A
    Human ST13-28198TH Recombinant Human ST13 E.coli N/A
    Human ST13-2855H Recombinant Human ST13 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ST13-337H Recombinant Human Suppression of Tumorigenicity 13 (Colon Carcinoma) (Hsp70 Interacting Protein) E.coli N/A
    Mouse ST13-16059M Recombinant Mouse ST13 Protein Mammalian Cell His
    Rat ST13-5766R Recombinant Rat ST13 Protein Mammalian Cell His
    Rhesus Macaque ST13-4496R Recombinant Rhesus monkey ST13 Protein, His-tagged Mammalian Cell His
    Chicken ST13-2458C Recombinant Chicken ST13 Mammalian Cell His
    Zebrafish ST13-10158Z Recombinant Zebrafish ST13 Mammalian Cell His

    ST13 involved in several pathways and played different roles in them. We selected most pathways ST13 participated on our site, such as Cellular response to heat stress, Cellular responses to stress, Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular response to heat stress NUP50; DPF1; HSPA12B; NUPL2; ST13; HDAC6; RPS19BP1; HSPA13; KIAA1967; HSPA14
    Cellular responses to stress Txn1; MOV10; NUP35; HMGA1B; HSPA7; GABARAPL2; KDM6B; RBBP7; CBX8; HBXIP
    Regulation of HSF1-mediated heat shock response HSPA14; ST13; KIAA1967; BAG3; HSPH1; HSPA13; DNAJB6; DNAJC7; HSPA12B; RPS19BP1

    ST13 has several biochemical functions, for example, Hsp70 protein binding, chaperone binding, dATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ST13 itself. We selected most functions ST13 had, and list some proteins which have the same functions with ST13. You can find most of the proteins on our site.

    Function Related Protein
    Hsp70 protein binding RPS3; PACRG; METTL21A; PPEF2; CDKN1B; TFRC; PPID; PARK2; MVD; ST13
    chaperone binding GNB5; DNAJA1; BAG4; CALR; TIMM44; PARK2; SOD1; SERPINA7; BAK1; BAG3
    dATP binding ERCC3; HSP90AB1; ST13
    identical protein binding LZTFL1; DRD4; IL12B; RCAN1; MAP1S; PFKL; TYSND1; SMAD3; GM5077; FHL2
    protein binding RRAGA; EIF1AX; RBM26; MT1G; ERCC6L; ELANE; RPIA; LSM5; KIAA1609; MOBP
    protein binding, bridging DSP; NCK1; MMS19; ADAP2; FSCN2B; RAD50; DDX20; SYNM; SPRR1B; FSCN3
    protein complex binding RAP1A; PTCH1; NCK2; ATM; FADD; GIT2; VPS28; PPP2R2A; RNF40; KHDRBS1
    protein domain specific binding YWHAH; SNCA; BHLHE40; YWHAQB; CACNB2; ODF1; STXBP1; TFDP1; PTPN11; IST1
    unfolded protein binding DNAJB1A; AFG3L2; DNAJA2L; PPIA; CHAF1B; CCT3; DNAJA1; DNAJA4; DNAJB6; TRAP1

    ST13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST13 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST13.

    BAG1; APOE; NOS3; PSEN1; TNF; NME2; GABARAPL2; PCBD1; IKBKE; TNFRSF14; PINX1; MAP3K3; PRKAB1

    Sugiyama, T; Sakaguchi, T; et al. Electron Microscopy and X-ray Analysis of Cr-Containing Precipitates Synthesized by Newly Isolated Actinobacterium, Flexivirga alba ST13(T). INDIAN JOURNAL OF MICROBIOLOGY 54:358-360(2014).
    AL Assaf, C; Lierman, E; et al. Screening of JAK2 V617F and MPL W515 K/L negative essential thrombocythaemia patients for mutations in SESN2, DNAJC17, ST13, TOP1MT, and NTRK1. BRITISH JOURNAL OF HAEMATOLOGY 165:734-737(2014).

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