STK24

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STK24

Official Full Name serine/threonine kinase 24
Background The yeast Sterile 20 gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In;mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation.;Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory;domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM;603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain;without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 (PubMed;10644707)).
Synonyms STK24; serine/threonine kinase 24; serine/threonine kinase 24 (Ste20, yeast homolog); serine/threonine-protein kinase 24; MST 3; MST3; MST3B; STE20; STE20 like kinase 3; sterile 20 like kinase 3; STK3; STE20-like kinase 3; STE20-like kinase MST3; sterile
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Stk24-6185M Recombinant Mouse Stk24 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human STK24-6559H Recombinant Human STK24 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human STK24-1359H Recombinant Human STK24, His tagged Insect Cell His
    Human STK24-2962H Recombinant Human STK24 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human STK24-362H Recombinant Human STK24, GST-tagged, Active Sf9 Insect Cell GST
    Human STK24-490HCL Recombinant Human STK24 cell lysate Insect Cell N/A
    Rat STK24-5792R Recombinant Rat STK24 Protein Mammalian Cell His
    Rhesus Macaque STK24-4526R Recombinant Rhesus monkey STK24 Protein, His-tagged Mammalian Cell His
    Chicken STK24-2514C Recombinant Chicken STK24 Mammalian Cell His

    STK24 involved in several pathways and played different roles in them. We selected most pathways STK24 participated on our site, such as Apoptosis, Apoptotic cleavage of cellular proteins, Apoptotic execution phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with STK24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Apoptosis PRKACBA; CSF2RB; H1F0; IRAK3; PPP3CC; HRK; SPNA2; PRKACB; PPP3R1B; CASP3B
    Apoptotic cleavage of cellular proteins CASP6L2; SATB1; DBNL; CLSPN; DSG2; OCLN; SPNA2; CTNNB1; LMNB1; DBNLA
    Apoptotic execution phase OCLN; DBNLB; HMGB2; DNM1L; HIST1H1D; CASP6L1; STK24; DSP; SATB1; PTBP3
    Programmed Cell Death BCAP31; STK24; BAXB; DIABLOA; DSP; GZMF; DSG2; SATB1; DNM1L; RNF8

    STK24 has several biochemical functions, for example, ATP binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STK24 itself. We selected most functions STK24 had, and list some proteins which have the same functions with STK24. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ACVR1L; CLPXA; TRIP13; PIM1; PYGL; MASTL; TXK; STK32B; MAPK12B; LIG1
    metal ion binding SDHC; ESR2B; RASSF5; CYP26C1; ZNF599; OAS3; ZNF577; COX5B; LHX8A; KDM7AB
    protein binding KIF2A; TEAD1; CUBN; DGAT1; CCKBR; CCR5; KEL; RAB24; BBS13; CIB1
    protein kinase activity TNNI3K; RPS6KA3; PRKCDA; STK4; PTK6B; RPS6KB2; SRPK1A; SRPK1; PTK7A; MAPK14A
    protein serine/threonine kinase activity PAK2A; DSTYK; SLK; MAP2K4; NEK8; HIPK1; PKZ; MAP2K5; PKMYT1; PAK4

    STK24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STK24 here. Most of them are supplied by our site. Hope this information will be useful for your research of STK24.

    PDCD10; STRN3; SLMAP

    Lasota, J; Kowalik, A; et al. Detection of the BRAF V600E Mutation in Colon Carcinoma Critical Evaluation of the Imunohistochemical Approach. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 38:1235-1241(2014).
    Dugast, E; Kiss-Toth, E; et al. Identification of Tribbles-1 as a Novel Binding Partner of Foxp3 in Regulatory T Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 288:10051-10060(2013).

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