STMN2
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Official Full Name
stathmin-like 2
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Overview
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Downs syndrome and Alzheimers disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. -
Synonyms
STMN2; stathmin-like 2; SCGN10; stathmin-2; SCG10; Neuronal growth associated protein; Protein SCG10; SCG 10; SCG10 protein; SCGN 10; SGC 10; SGC10; Stathmin 2; Stathmin like 2; STMN 2; STMN2_HUMAN; Superior cervical ganglia neural specific 10; Superior cervical ganglion 10 protein; Superior cervical ganglion-10 protein; Superiorcervical ganglia neural specific 10; OTTHUMP00000226983; OTTHUMP00000226984; OTTHUMP00000227682; neuron-specific growth-associated protein; superior cervical ganglia, neural specific 10; neuronal growth-associated protein (silencer element);
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- SUMO
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- STMN2 Related Research Area
STMN2 involved in several pathways and played different roles in them. We selected most pathways STMN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with STMN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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STMN2 has several biochemical functions, for example, calcium-dependent protein binding, protein binding, tubulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STMN2 itself. We selected most functions STMN2 had, and list some proteins which have the same functions with STMN2. You can find most of the proteins on our site.
Function | Related Protein |
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calcium-dependent protein binding | KCNIP3;STX2;VLDLR;ANXA11;STX1A;CHP;FCN2;STMN2;CHP1 |
protein binding | SIGLEC6;SPATA2;ARNTL1B;HHEX;THBD;ZNF543;TNPO3;TLR2;SPTLC1 |
tubulin binding | GPAA1;AGBL5;NCALD;PRNP;TPPP;STMN3;RABGAP1;BRCA1;ATF5 |
STMN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STMN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of STMN2.
TEX11; TXLNA; TFCP2; NGFR; EEF1A1; GCNT1; CEP70; VOPP1; GPRASP2; CCDC85A
- Q&As
- Reviews
Q&As (5)
Ask a questionGene therapy targeting STMN2 expression could be explored as a potential approach, but its feasibility and safety would need thorough investigation.
Yes, targeting STMN2 could be a potential therapeutic strategy for neurodegenerative diseases by modulating microtubule dynamics and neuronal function.
STMN2 regulates microtubule stability and dynamics, influencing processes such as axon growth, guidance, and synaptic plasticity during neuronal development.
STMN2 overexpression has been linked to cancer progression by promoting microtubule destabilization, cell proliferation, and migration.
STMN2 levels may serve as a potential diagnostic biomarker for certain neurological disorders, but further research is needed to establish its diagnostic utility.
Customer Reviews (3)
Write a reviewThe STMN2 protein showcases outstanding quality, ensuring its suitability for addressing my experimental requirements effectively.
Its top-notch purity and integrity instill confidence in obtaining precise and reliable data, thereby enabling significant advancements in my research.
The manufacturer's dedication to excellent technical support assures me that any challenges or obstacles I encounter will be swiftly resolved.
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