• Official Full Name
  • syntaxin 16
  • Background
  • This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1)gene.
  • Synonyms
  • STX16; syntaxin 16; syntaxin-16; hsyn16; SYN16
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey STX16 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken STX16
Source (Host):Species:Human
Product nameRecombinant Human STX16 293 Cell Lysate

Involved Pathway

STX16 involved in several pathways and played different roles in them. We selected most pathways STX16 participated on our site, such as SNARE interactions in vesicular transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
SNARE interactions in vesicular transport

Protein Function

STX16 has several biochemical functions, for example, SNAP receptor activity, protein binding, syntaxin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX16 itself. We selected most functions STX16 had, and list some proteins which have the same functions with STX16. You can find most of the proteins on our site.
Related Protein
Function SNAP receptor activity
Related Protein STX11B.1; VAMP3; VTI1B; STX5A; VAMP4; GOSR2; SEC22BB; GS15; SEC22A; VAMP2
Function protein binding
Related Protein LIN28A; DNAJC10; CDK11B; FEN1; ALAS1; ZBTB17; TREML2; FAM72A; SUN1; IL2RG
Function syntaxin binding
Related Protein SNAP23; VPS11; SYT5A; CPLX3B; VPS52; SNAP23.2; SYTL1; STX8; NAPGA; STXBP4

Interacting Protein

STX16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX16 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX16.
MEOX2; VAMP5; STX4; NAPB; PTPN12; rpoN; pi3p

STX16 Related Articles

Andersson, SA; Pedersen, MG; et al. Glucose-dependent docking and SNARE protein-mediated exocytosis in mouse pancreatic alpha-cell. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 462:443-454(2011).
Ng, EL; Wang, Y; et al. Rab22B's role in trans-Golgi network membrane dynamics. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 361:751-757(2007).