stx8
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  • Official Full Name
  • syntaxin 8
  • Background
  • The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • STX8; syntaxin 8; syntaxin-8; CARB; STX 8; Syntaxin8; CIP-1-associated regulator of cyclin B
Cat.#:STX8-3033HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STX8, GST-tagged
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Cat.#:STX8-349HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human STX8, His tagged
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Cat.#:STX8-545HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STX8 Protein
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Cat.#:STX8-16195MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse STX8 Protein
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Cat.#:STX8-5818RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat STX8 Protein
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Cat.#:STX8-4550RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey STX8 Protein, His-tagged
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Cat.#:STX8-2401CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken STX8
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Cat.#:STX8-10693ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish STX8
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Cat.#:STX8-1030HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human STX8 cell lysate
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Involved Pathway

STX8 involved in several pathways and played different roles in them. We selected most pathways STX8 participated on our site, such as SNARE interactions in vesicular transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
SNARE interactions in vesicular transport
STX5; GOSR1; VAMP8; SEC22B; STX11; BET1L; STX11A; VAMP2; GS15; STX11B.1

Protein Function

STX8 has several biochemical functions, for example, chloride channel inhibitor activity, protein binding, syntaxin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX8 itself. We selected most functions STX8 had, and list some proteins which have the same functions with STX8. You can find most of the proteins on our site.
Function
Related Protein
Function chloride channel inhibitor activity
Related Protein WNK1; VAMP8; STX8; STX1A; STX7; VTI1B; CFTR
Function protein binding
Related Protein CCDC167; C9orf142; TBCA; JAM2A; NR4A3; KIR2DL1; RIMS2; NKX3-1; HCLS1; SULT1A3
Function syntaxin binding
Related Protein SNAP29; CPLX4C; SNAP47; CPLX4A; SYT11; SYT7; VPS18; NAPAA; BET1; STXBP1
Function ubiquitin protein ligase binding
Related Protein TRIM28; AXIN1; TP53; PTPN22; RANGAP1; ATXN3; BCL2; NEDD8; PRR5L; UBXN1

Interacting Protein

STX8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX8 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX8.
STX4; CREB3; VTI1B; NSF; WDR91; GAMMAHV.ORF30; GAMMAHV.ORF35; carB; prfB; rbsK; q81x37_bacan; q99ib8-pro_0000045598; Sec24c; VAMP4; ATP6V1A; VAMP7