The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex.
SYCP2; synaptonemal complex protein 2; SCP2; hsSCP2; SCP 2; SCP-2; SYCP2_HUMAN; Synaptonemal complex lateral element protein
SYCP2 involved in several pathways and played different roles in them. We selected most pathways SYCP2 participated on our site, such as Cell Cycle, Meiosis, Meiotic synapsis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYCP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
SYCP2 has several biochemical functions, for example, DNA binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SYCP2 itself. We selected most functions SYCP2 had, and list some proteins which have the same functions with SYCP2. You can find most of the proteins on our site.
Function DNA binding
Related Protein ZFP36L3; LEF1; KLF14; CEBPA; NFIX; HER12; NR1H2; SIM1; ASCL5; NFE2L2B
Function protein heterodimerization activity
Related Protein Pdgfa&Pdgfb; YWHAE; NEUROD1; CLNS1A; MEIS1; SUPT5H; ZBTB1; DMBX1; XBP1; UGT1A2
SYCP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYCP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYCP2.
SYCP2 Related Articles
Khajavi, N; Akbari, M; et al. Role of Somatic Testicular Cells during Mouse Spermatogenesis in Three-Dimensional Collagen Gel Culture System. CELL JOURNAL 16:79-90(2014).
Merico, V; Gimenez, MD; et al. Chromosomal speciation in mice: a cytogenetic analysis of recombination. CHROMOSOME RESEARCH 21:523-533(2013).