tac3
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  • Official Full Name
  • tachykinin 3
  • Background
  • This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily;expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand;for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may;be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with;normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants.
  • Synonyms
  • TAC3; tachykinin 3; neurokinin beta , neuromedin K , NKNB; tachykinin-3; NKB; ZNEUROK1; neuromedin K; gamma tachykinin 3; preprotachykinin B; NKNB; PRO1155
Cat.#:TAC3-29652THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TAC3, His-tagged
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Cat.#:TAC3-29653THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TAC3, His-tagged
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Cat.#:TAC3-3093HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TAC3, GST-tagged
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Cat.#:TAC3-79HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Tachykinin 3, His-tagged
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Cat.#:Tac3-5805RTag:His|GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Tac3 protein, His & GST-tagged
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Cat.#:TAC3-1287HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TAC3 293 Cell Lysate
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Involved Pathway

TAC3 involved in several pathways and played different roles in them. We selected most pathways TAC3 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)
POMCB; PROK2; OXTRL; APLNR; HEBP1; LPAR1; HRH3; CGA; CCR5; FPR-RS3
G alpha (q) signalling events
QRFP; CASR; EDNRB; PROKR1A; MGLL; KALRNB; LTB4R; EDN3; GPR68; FFAR3
GPCR downstream signaling
FFAR3; RASGRP2; APLN; ANXA1; CRHR2; GPR68; NET1; NMU; RXFP2B; OR56A1
GPCR ligand binding
INSL3; LPAR2A; OPN1LW1; GNB5A; CALCB; PENK; EMR4; UTS2; RAMP3; TAS2R7
Gastrin-CREB signalling pathway via PKC and MAPK
PROKR1A; MLN; ANXA1C; CCK; KISS1; NMS; OPN4B; ABHD6B; EDN3; GPR65
Peptide ligand-binding receptors
INSL3; NMBB; EDNRAB; NMS; TRH; INSL5; CCBP2; NPFF; PROK2; SSTR1
Signal Transduction
PTGDR2; USP9; WDR35; SHRPRBCK1R; FSTL1B; CRABP1A; EVL; GPR68; PRC1B; BCO2
Signaling by GPCR
RLN2; XK; OXGR1A.1; CCK; OR7D2; GPR120; SST1.1; RGS18; OPN4B; OPN4.1

Protein Function

TAC3 has several biochemical functions, for example, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAC3 itself. We selected most functions TAC3 had, and list some proteins which have the same functions with TAC3. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein TSPAN6; ASIC1; LAT2; STK36; ARHGEF2; PRKAB1; CNTNAP4; HES1; PWWP2B; AHSP
Function receptor binding
Related Protein SRMS; AMH; HLA-E; UCN2; FGF13A; TAC3; CADM1; DAO1; PPP2R4; NRG2B

Interacting Protein

TAC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAC3.
IKBKAP; PTN; UBR1; VOPP1; FEZ1; CCDC90B

TAC3 Related Articles

Bahadory, F; Moore, KH; et al. Gene expression of nnuscarinic, tachykinin, and purinergic receptors in porcine bladder: comparison with cultured cells. FRONTIERS IN PHARMACOLOGY 4:-(2013).
Mostafa, GA; Al-Ayadhi, LY; et al. The possible link between the elevated serum levels of neurokinin A and anti-ribosomal P protein antibodies in children with autism. JOURNAL OF NEUROINFLAMMATION 8:-(2011).