TAP1
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Official Full Name
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
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Overview
CRTAP is found in articular chondrocytes and is expressed in a variety of other tissues. Defects in CRTAP are the cause of osteogenesis imperfecta type 7 (OI-7). OI is a connective tissue disorder characterized by bone fragility and low bone mass. OI-7 is an autosomal recessive form of OI. -
Synonyms
TAP1; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP); APT1; PSF1; ABC17; ABCB2; RING4; TAP1N; D6S114E; FLJ26666; FLJ41500; TAP1*0102N; ABC 17; ATP binding cassette sub family B (MDR/TAP) member 2; ATP binding cassette transporter; Peptide transporter PSF 1; Transporter 1 ATP binding cassette sub family B (MDR/TAP); Peptide supply factor 1; Really interesting new gene 4 protein2; PSF-1; antigen peptide transporter 1; ABC transporter, MHC 1; transporter, ATP-binding cassette, major histocompatibility complex, 1Y3; transporter associated with antigen processing;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Rat
- E.coli
- E.Coli or Yeast
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His|T7
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | TAP1-7882H | Recombinant Human TAP1 protein, His & T7-tagged | E.coli | His/T7 | Tyr525~Glu808 (Accession # Q03518) | |
Human | TAP1-3512H | Recombinant Human TAP1, His-tagged | E.Coli or Yeast | His | 808 | |
Human | TAP1-3113H | Recombinant Human TAP1, GST-tagged | E.coli | GST | C-term-300aa | |
Human | TAP1-1254HCL | Recombinant Human TAP1 293 Cell Lysate | HEK293 | N/A | ||
Human | TAP1-6821HF | Recombinant Full Length Human TAP1 Protein, GST-tagged | In Vitro Cell Free System | GST | 808 amino acids | |
Human | TAP1-6397H | Recombinant Human TAP1 Protein (Tyr525-Glu808), N-His tagged | E.coli | N-His | Tyr525-Glu808 | |
Human | TAP1-675H | Recombinant Human TAP1 Protein, GST-tagged | Wheat Germ | GST | 1-808 aa | |
Rat | Tap1-3511R | Recombinant Rat Tap1, His-tagged | E.Coli or Yeast | His | 725 | |
Chicken | TAP1-3878C | Recombinant Chicken TAP1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- TAP1 Related Articles
TAP1 involved in several pathways and played different roles in them. We selected most pathways TAP1 participated on our site, such as ABC transporters, Phagosome, Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ABC transporters | ABCB6;ABCC5;ABCA1B;CFTR;ABCD4;ABCG1;ABCG2;ABCB11;ABCD3A |
Phagosome | FCGR2C;STX7;HLA-A;DYNC1LI2;RAB5AB;BLB1;RAB7;CD14;TUBA7L |
Antigen processing and presentation | HSPA2;IFNG;CANX;PSME2;RFX5;NFYA;KLRC2;CD8B;HLA-G |
Herpes simplex infection | CFP;IFIH1;HCFC1B;IFNG;MAPK8;Casp3;BLA;IL12BA;PPP1CC |
Primary i | PTPRC;BLNK;CD79A;CD8A;CD40LG;CD19;BTK;IKBKG;AICDA |
nodeficiency | PTPRC;IKBKG;CD8A;ZAP70;ICOS;RFX5;TNFRSF13B;RAG1;TAP2 |
TAP1 has several biochemical functions, for example, ADP binding, ATP binding, ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by TAP1 itself. We selected most functions TAP1 had, and list some proteins which have the same functions with TAP1. You can find most of the proteins on our site.
Function | Related Protein |
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ADP binding | ADCK3;GLUD1;ABCG1;GLUD2;PRKAG1;VCP;PRPS2;CYB5R3;ACTA1 |
ATP binding | MLH3;LARS;SUCLG1;CSF1R;VMHCL;PIP5K2;RAD50;ERBB4A;PRKACBA |
ATPase activity, coupled to transmembrane movement of substances | ABCG8;IPO8;ABCG2D;ABCB4;ABCB10;ABCC2;ABCD1;ABCB6A;ABCB5 |
MHC class I protein binding | DERL1;ATP5A1;CD8A;HLA-E;TAPBP;LILRB2;PILRB;CD8B;PILRB2 |
MHC class Ib protein binding | TAP2;LILRB2;TAP1 |
TAP1 binding | HLA-F;TAPBP;TAP2;TAP1 |
TAP2 binding | TAP1;TAPBP;HLA-F |
peptide antigen binding | MHC1UBA;MHC1UKA;H2-AA;H2-AB1;MHC1UIA;TAPBP;MHC1UHA;MHC1UDA;HLA-DRB3 |
contributes_to peptide transporter activity | TAP2;TAP1 |
peptide transporter activity | TAP1;DISP1 |
peptide-transporting ATPase activity | TAP1;ABCB9 |
protein binding | USP1;GSTO1;TBCA;MATN3;DDX58;VAMP7;FPR1;CRHR1;ID3 |
protein heterodimerization activity | KCNH1;H2AFV;SNX5;TPD52;AHR;P4HB;DRD1;INHA;H2-AA |
protein homodimerization activity | VEGFA;ABCG2;S100A6;ZNF174;SDCBP2;CBX5;GM5506;DRD2;TRIM8 |
tapasin binding | TAP1;TAP2 |
TAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAP1.
TAP2; TAPBP
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