|Official Full Name||transcription factor 7-like 1 (T-cell specific, HMG-box)|
|Background||This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.|
|Synonyms||TCF7L1; transcription factor 7-like 1 (T-cell specific, HMG-box); TCF3; transcription factor 7-like 1; OTTMUSP00000023419; T cell factor 3; TCF 3; bHLHb21; HMG box transcription factor; Transcription factor 7 like 1 (T-cell specific, HMG-box); Transcription factor 7 like 1; OTTHUMP00000160497; HMG box transcription factor 3; TCF-3|
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TCF7L1 involved in several pathways and played different roles in them. We selected most pathways TCF7L1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TCF7L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
TCF7L1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TCF7L1 itself. We selected most functions TCF7L1 had, and list some proteins which have the same functions with TCF7L1. You can find most of the proteins on our site.
TCF7L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TCF7L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TCF7L1.