THNSL2 Protein, threonine synthase-like 2


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Official Full Name threonine synthase-like 2
Background This gene encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants.
Synonyms THNSL2; threonine synthase-like 2 (S. cerevisiae); threonine synthase-like 2; FLJ10916; secreted osteoclastogenic factor of activated T cells; secreted osteoclastogenic factor of activated T-cells; THS2; TSH2; SOFAT; FLJ35504
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human THNSL2-890H Recombinant Human THNSL2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse THNSL2-16747M Recombinant Mouse THNSL2 Protein Mammalian Cell His
    Rat THNSL2-6053R Recombinant Rat THNSL2 Protein Mammalian Cell His
    Zebrafish THNSL2-3551Z Recombinant Zebrafish THNSL2 Mammalian Cell His

    THNSL2 involved in several pathways and played different roles in them. We selected most pathways THNSL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with THNSL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    THNSL2 has several biochemical functions, for example, (-)-E-beta-caryophyllene synthase activity, (E)-beta-ocimene synthase activity, alpha-humulene synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by THNSL2 itself. We selected most functions THNSL2 had, and list some proteins which have the same functions with THNSL2. You can find most of the proteins on our site.

    Function Related Protein
    (-)-E-beta-caryophyllene synthase activity THNSL2
    (E)-beta-ocimene synthase activity THNSL2
    alpha-humulene synthase activity THNSL2
    lyase activity ALDOAA; Car4; GC2; ACLYA; CAHZ; ADCY2B; THA1; CTHL; GUCY2E; ADCY1B
    pyridoxal phosphate binding MARC1; ACCS; PYGB; SPTLC2; CBSB; GPT2L; Alb; GAD2; SHMT1; PYGMB
    sabinene synthase activity THNSL2
    serine binding SHMT1; THNSL2; GRM7

    THNSL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with THNSL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of THNSL2.


    Hotta, K; Kitamoto, A; et al. Replication Study of 15 Recently Published Loci for Body Fat Distribution in the Japanese Population. JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS 20:336-350(2013).
    Fox, CS; Liu, YM; et al. Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women. PLOS GENETICS 8:-(2012).
    Mason, CC; Hanson, RL; et al. Bimodal distribution of RNA expression levels in human skeletal muscle tissue. BMC GENOMICS 12:-(2011).

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