|Official Full Name||transducin-like enhancer of split 3, homolog of Drosophila E(spl)|
|Synonyms||ESG; Grg3a; Grg3b; mKIAA1547; 2610103N05Rik|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
TLE3 involved in several pathways and played different roles in them. We selected most pathways TLE3 participated on our site, such as Deactivation of the beta-catenin transactivating complex, Degradation of beta-catenin by the destruction complex, Formation of the beta-catenin:TCF transactivating complex, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLE3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Deactivation of the beta-catenin transactivating complex||TLE2; BCL9; PYGO1; RBBP5; SOX9A; TLE4; TLE3; CBY1; PYGO2; CTBP1|
|Degradation of beta-catenin by the destruction complex||AES; CTBP1; TLE3; CTBP2; TLE3B; TLE4; TLE2; TLE1; FAM123B|
|Formation of the beta-catenin:TCF transactivating complex||BCL9; TLE3; RBBP5; PYGO2; CDC73; ASH2L; TLE3B; TLE1; TLE2; TLE4|
|NOTCH1 Intracellular Domain Regulates Transcription||TUBB3; HEYL; TLE4; TLE2; TLE1; HEY2; HEY1; TLE3|
|Repression of WNT target genes||TLE3; TLE3B; AES; TLE4; TLE2|
|Signal Transduction||RHOU; SCT; ARHGAP1; EMR4; GUCA1E; CCK; SHRPRBCK1R; PRKCHB; PTHLH; PDE10A|
|Signaling by NOTCH||RAB6A; MDK; TLE4; DNER; TLE3; TLE2; MDKA; DLK1; DTX2; HEYL|
|Signaling by NOTCH1||DLK1; TLE3; HEYL; DNER; DTX2|
TLE3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TLE3 itself. We selected most functions TLE3 had, and list some proteins which have the same functions with TLE3. You can find most of the proteins on our site.
|protein binding||GADD45B; SFN; JAK3; TRAP1; FRS2; ASF1A; PRUNE; TCAP; DNMT3B; CEP104|
TLE3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TLE3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TLE3.
lnx2b; AES; HDAC1; tcf7l1a; q81qn9_bacan; q81qv1_bacan; ANXA1; CUL4B; NLK