tlr8
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  • Official Full Name
  • toll-like receptor 8
  • Background
  • Toll like receptor 8 (TLR8) family in mammals is comprised of a family of transmembrane proteins which contain multiple leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domains. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120 kDa.
  • Synonyms
  • TLR8; toll-like receptor 8; CD288; MGC119599; MGC119600
Cat.#:TLR8-902HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TLR8 protein, His-tagged
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Cat.#:TLR8-930HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human TLR8 protein, His-tagged
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Cat.#:TLR8-16830MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TLR8 Protein
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Cat.#:Tlr8-2079RTag:His|T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Tlr8 protein, His & T7-tagged
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Cat.#:TLR8-4737RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TLR8 Protein, His-tagged
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Involved Pathway

TLR8 involved in several pathways and played different roles in them. We selected most pathways TLR8 participated on our site, such as Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLR8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Toll-like receptor signaling pathway
PIK3R3A; TLR2-2; TAB2; PIK3R3B; FADD; FOS; IFNA8; RIPK1L; IFNA4; MAPK8

Protein Function

TLR8 has several biochemical functions, for example, DNA binding, double-stranded RNA binding, drug binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TLR8 itself. We selected most functions TLR8 had, and list some proteins which have the same functions with TLR8. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein TEAD2; PAX2A; LIN28A; MKXA; KIN; NEUROD6A; CEBPZ; SP140; DDX41; ZNF350
Function double-stranded RNA binding
Related Protein TARBP2; DHX36; DROSHA; AGO1; SLC3A2; LRRFIP1; DHX30; MTDH; ILF3; EIF2AK2
Function drug binding
Related Protein P2RX2; FNTB; CHRM1; PIGC; SLC6A4A; ADH1; PPARD; HTR2A; SMO; CHRM3
Function single-stranded RNA binding
Related Protein SNRPC; CBX7; LUZP4; CBX6; TLR7; ZFP36; PIWIL1; AGO2; STRBP; TLR8