TNKS2

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TNKS2

Official Full Name tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Synonyms TNKS2; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; PARP 5b; PARP 5c; PARP5B; PARP5C; pART6; TANK2; TNKL; TNKS-2; tankyrase 2; tankyrase II; tankyrase-like protein; tankyrase-related protein; poly [ADP-ribose] polymerase 5B; TRF1-interacting ankyrin-related ADP-ribose polymerase 2; PARP-5b; PARP-5c
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TNKS2-3328H Recombinant Human TNKS2, GST-tagged E.coli GST
    Human TNKS2-3329H Recombinant Human TNKS2 protein, GST-tagged Wheat Germ GST
    Human TNKS2-8199H Recombinant Human TNKS2 protein, His-tagged E.coli His
    Mouse TNKS2-17189M Recombinant Mouse TNKS2 Protein Mammalian Cell His
    Rhesus Macaque TNKS2-4879R Recombinant Rhesus monkey TNKS2 Protein, His-tagged Mammalian Cell His
    Chicken TNKS2-5913C Recombinant Chicken TNKS2 Mammalian Cell His
    Kit-1884 TNKS2 Histone Ribosylation Assay Kit (Antibody Detection) I N/A
    Kit-1885 TNKS2 Histone Ribosylation Assay Kit (Antibody Detection) II N/A
    Kit-1886 TNKS2 Histone Ribosylation Assay Kit (Biotin-labeled NAD+) I N/A
    Kit-1887 TNKS2 Histone Ribosylation Assay Kit (Biotin-labeled NAD+) II N/A
    Kit-1888 TNKS2 Histone Ribosylation Colorometric Assay Kit N/A

    TNKS2 involved in several pathways and played different roles in them. We selected most pathways TNKS2 participated on our site, such as Degradation of AXIN, Disease, Diseases of signal transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNKS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Degradation of AXIN TNKS2; TNKS; RNF146
    Disease FGFR1OP2; PDCD6IP; SFTPC; ANTXR1; HEY2; HEYL; PSIP1; PPIAL4A; OPN1SW; DPF1
    Diseases of signal transduction KREMEN2; MIB1; RBP4; CTBP2; CUX1; RBP1; DERL2; HEYL; OPN1LW; HEY2
    Signal Transduction PROKR1; OPN1SW1; APLNR; NCKIPSD; ARHGAP40; RNF43; CHRDL1; NMU; RHOU; ARHGEF17
    Signaling by WNT in cancer KREMEN2; RNF43; KREMEN1; TNKS2; TNKS
    Signaling by Wnt SOX9A; RNF43; SRY; RSPO4; KREMEN2; ASH2L; SOX32; RSPO2; C; SOX9B
    TCF dependent signaling in response to WNT ZNRF3; PYGO1; SOX13; SOX4A; SOX9B; RBBP5; RSPO3; LGR4; SRY; SOX9A
    XAV939 inhibits tankyrase, stabilizing AXIN TNKS2

    TNKS2 has several biochemical functions, for example, NAD+ ADP-ribosyltransferase activity, enzyme binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNKS2 itself. We selected most functions TNKS2 had, and list some proteins which have the same functions with TNKS2. You can find most of the proteins on our site.

    Function Related Protein
    NAD+ ADP-ribosyltransferase activity PARP12A; PARP1; GIG2J; PARP9; PARP8; CHAT1; PARP14; PARP15; GIG2P; GIG2Q
    enzyme binding PRMT1; U2AF2; CYP1A2; HLCS; YWHAB; H2AFX; BRCA1; LDB1; TSPAN5; DDX5
    metal ion binding CA4A; CLCNKA; ZBTB43; ZGPAT; ZNF653; AMDHD2; ZNF177; ZFYVE28; REV1; BCMO1
    protein binding RBBP8; RRAGD; HRK; PSEN2; IQCE; HSPA6; NDEL1; TULP3; RPRD1B; LTC4S

    TNKS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNKS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNKS2.

    Sh3bp2; SH3BP2; BCR; RAD54L; BABAM1

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