TRIM32

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TRIM32

Official Full Name tripartite motif containing 32
Background The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
Synonyms TRIM32; tripartite motif containing 32; LGMD2H, limb girdle muscular dystrophy 2H (autosomal recessive) , tripartite motif containing 32; E3 ubiquitin-protein ligase TRIM32; BBS11; HT2A; TATIP; 72 kda Tat interacting Protein; LGMD2H; Limb girdle muscular dystrophy 2H (autosomal recessive); Limb girdle muscular dystrophy 2H; Muscular dystrophy Hutterite type; TAT interactive protein 72KD; Tripartite Motif Containing Protein 32; Zinc Finger Protein HT2A; OTTHUMP00000022763; zinc-finger protein HT2A; 72 kDa Tat-interacting protein; TAT-interactive protein, 72-KD; tripartite motif-containing 32; tripartite motif-containing protein 32
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM32-4773H Recombinant Human TRIM32 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Trim32-6653M Recombinant Mouse Trim32 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human TRIM32-198H Recombinant Human TRIM32, GST-tagged Sf9 Insect Cell GST
    Human TRIM32-782HCL Recombinant Human TRIM32 293 Cell Lysate HEK293 N/A
    Rhesus Macaque TRIM32-4962R Recombinant Rhesus monkey TRIM32 Protein, His-tagged Mammalian Cell His
    Zebrafish TRIM32-6330Z Recombinant Zebrafish TRIM32 Mammalian Cell His

    TRIM32 involved in several pathways and played different roles in them. We selected most pathways TRIM32 participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM32 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis RNF7; UBE2D1; SOCS1A; CDC23; TRIP12; UBE2K; UBE2KA; UBE2D2; FBXO2; KLHL9

    TRIM32 has several biochemical functions, for example, RNA binding, Tat protein binding, ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM32 itself. We selected most functions TRIM32 had, and list some proteins which have the same functions with TRIM32. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding TRIM71; RTCD1; HENMT1; SAMD4; PCBP2; RBM6; CPSF5; SFSWAP; ZNF638; Aff2
    Tat protein binding TRIM32; MDFIC; SMARCA4; SMARCB1; DLL1; GABARAPL1; NPM1; ACTB
    ligase activity MARCH1; NAPRT1; NAPRT; HERC6; RNF212; HUWE1; UBE2G1B; CNOT4; TRIML1; UBE2I
    myosin binding DMD; ACTC1; CALM; STX4A; VAMP2; USH2A; RHOA; VETZ; TRIM32; GIPC1
    protein binding NUF2; MTPAP; HPS1; MASP1; SPP1; SRP14; PPARG; HPN; BIRC7; ARNTL
    protein self-association AGTR1A; CCL5; TMEM43; CTSB; AGXT; TMEM190; NKX3; SVIP; PCSK9; SYP
    transcription coactivator activity TUBB3; TFDP1A; CD3D; TAF6L; HSF2; SP4; MYOCD; CRSP7; POU2AF1; ABT1
    translation initiation factor binding LARP1; ZNF259; POLR2G; EIF3BA; EIF2B3; EIF3C; CELF1; EIF3B; POLR2D; EIF2B5
    ubiquitin binding UBE2NB; VPS36; VPS28; C36E6.2; SIRT2; D17WSU92E; SMAD3; DNAJC2; UBR5; TNFAIP3
    ubiquitin protein ligase activity NEDD4; UBE3A; LRSAM1; RNF152; PJA2; RNF165; TRIM71; CBLL1; XIAP; TRIM63
    ubiquitin-protein transferase activity BIRC7; MUL1; TRAF7; PEX12; RNF13; LRSAM1; RNF43; PDZRN3; UBE2K; MGRN1
    zinc ion binding MARCH11; ADAM12; BTR18; MT1A; RNF43; HERC2; RABGEF1; CPXM1; LTA4H; ABLIM1B

    TRIM32 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM32 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM32.

    PDE9A; SCGB1A1; UBE2U; UBQLN1; b3kpu6_human

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