trim39
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  • Official Full Name
  • tripartite motif containing 39
  • Background
  • The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms.
  • Synonyms
  • TRIM39; tripartite motif containing 39; ring finger protein 23 , RNF23, tripartite motif containing 39; tripartite motif-containing protein 39; HGNC:10065; MGC32984; Ring finger protein 23; RNF23; Testis abundant finger protein; TFP; TFP RING FINGER PROTEIN 23; testis-abundant finger protein; tripartite motif-containing 39; TRIM39B
Cat.#:TRIM39-6277RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TRIM39 Protein
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Cat.#:TRIM39-1345CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TRIM39
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Cat.#:TRIM39-778HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TRIM39 293 Cell Lysate
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Involved Pathway

TRIM39 involved in several pathways and played different roles in them. We selected most pathways TRIM39 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM39 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
DYNC1I2; TRIM11; OSBPL1A; BTLA; UBE2F; KLHL21; PDPK1A; ERAP1; SIGLEC11; Siglece
Antigen processing: Ubiquitination &
SH3RF1; GAN; ASB13; HECTD3; LRSAM1; UBE2V2; DTX3L; UBE2E3; RNF182; ARIH2
Proteasome degradation
LRSAM1; RNF220; RNF123; SPSB2; SPSB1; TRIM11; HECTD3; UBE2E3; BLMH; ASB3
Class I MHC mediated antigen processing &
RNF34; TRIM9; DZIP3; RNF4; SH3RF1; TRIM41; TRIM69; PJA1; UBR2; ASB14
presentation
CTSL2; ASB7; WWP1; UBE2V2; GAN; UBE2E3; UFL1; B2ML; FBXO27; ASB6
Immune System
PJA1; RNF182; SRMS; SIGLEC8; LILRA1; CLEC5A; MGC174857; NPEPPS; HBL3; CTSO

Protein Function

TRIM39 has several biochemical functions, for example, identical protein binding, ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM39 itself. We selected most functions TRIM39 had, and list some proteins which have the same functions with TRIM39. You can find most of the proteins on our site.
Function
Related Protein
Function identical protein binding
Related Protein TPCN1; BNIP3L; SNCAIP; PON2; GRIN3A; FGFR1; GSTM3; SOD2; FBP1; MYBPC3
Function ligase activity
Related Protein UBE4B; TRIM37; RAD18; MEX3C; RNF144AB; XIAP; PRPF19; TRIM17; TRIML1; MGRN1
Function protein binding
Related Protein ZNF83; BCL6; GNAT1; GRM6; INTS12; CLSTN1; LASP1; CREB3L3; TLE2; STARD3
Function zinc ion binding
Related Protein SETMAR; MT1A; MMP30; ZCCHC10; RORC; RNF111; HNF4G; ANPEPB; TRIM2; CALB1

Interacting Protein

TRIM39 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM39 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM39.
UBE2D1; TRIM17; UBE2D3