• Official Full Name
  • tRNA isopentenyltransferase 1
  • Background
  • tRNA isopentenyltransferase, mitochondrial is an enzyme that in humans is encoded by the TRIT1 gene. It catalyzes the addition of an isopentenyl group from dimethylallyl diphosphate (DMAPP) onto adenosine residue 37 of certain tRNA molecules.
  • Synonyms
  • TRIT1; tRNA isopentenyltransferase 1; tRNA dimethylallyltransferase, mitochondrial; FLJ20061; IPT; 2310075G14Rik; AI314635; AV099619; MGC149242; MGC149243; mitochondrial; MOD5; AI314189; hGRO1; IPP transferase; IPPT; IPTase; Isopentenyl diphosphate:tRNA isopentenyltransferase; Isopentenyl-diphosphate:tRNA isopentenyltransferase; MOD5_HUMAN; OTTMUSP00000009314; Putative protein TR2IT1; RP23-121J14.6; TRIT 1; tRNA dimethylallyltransferase; tRNA isopentenylpyrophosphate transferase; tRNA isopentenyltransferase; tRNA isopentenyltransferase mitochondrial
Source (Host):HEK293Species:Human
Product nameRecombinant Human TRIT1 Protein, MYC/DDK-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIT1, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TRIT1 Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TRIT1
Source (Host):Species:Human
Product nameRecombinant Human TRIT1 cell lysate

Involved Pathway

TRIT1 involved in several pathways and played different roles in them. We selected most pathways TRIT1 participated on our site, such as Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolic pathways

Protein Function

TRIT1 has several biochemical functions, for example, ATP binding, metal ion binding, tRNA dimethylallyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIT1 itself. We selected most functions TRIT1 had, and list some proteins which have the same functions with TRIT1. You can find most of the proteins on our site.
Related Protein
Function ATP binding
Related Protein KIF5C; NEK3; CCT6B; Ckmm; MARK4; ATAD2B; DNAH6; MAP2K4; STK32B; KDRL
Function metal ion binding
Related Protein FBP1; ITGAV; GALNTL4; BCKDHA; GTF3A; NR1D2A; ZNF230; ZMYND17; ZNF193; FAM96A
Function tRNA dimethylallyltransferase activity
Related Protein TRIT1

Interacting Protein

TRIT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIT1.
C8orf30A; SMYD3

TRIT1 Related Articles

Lindner, AC; Lang, D; et al. Isopentenyltransferase-1 (IPT1) knockout in Physcomitrella together with phylogenetic analyses of IPTs provide insights into evolution of plant cytokinin biosynthesis. JOURNAL OF EXPERIMENTAL BOTANY 65:2533-2543(2014).
Lamichhane, TN; Mattijssen, S; et al. Human Cells Have a Limited Set of tRNA Anticodon Loop Substrates of the tRNA Isopentenyltransferase TRIT1 Tumor Suppressor. MOLECULAR AND CELLULAR BIOLOGY 33:4900-4908(2013).