tsen54
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  • Official Full Name
  • tRNA splicing endonuclease 54 homolog (S. cerevisiae)
  • Synonyms
  • RP23-354K2.5; 0610034P02Rik
Cat.#:TSEN54-2799HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human TSEN54 Protein, MYC/DDK-tagged
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Cat.#:TSEN54-17482MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TSEN54 Protein
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Cat.#:TSEN54-4991RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TSEN54 Protein, His-tagged
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Cat.#:TSEN54-2723ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TSEN54
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Cat.#:TSEN54-704HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human TSEN54 lysate
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Involved Pathway

TSEN54 involved in several pathways and played different roles in them. We selected most pathways TSEN54 participated on our site, such as Gene Expression, tRNA processing, tRNA processing in the nucleus, which may be useful for your reference. Also, other proteins which involved in the same pathway with TSEN54 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
ZNF223; PUS1; ZNF180; ZNF202; LSM11; METTL3; ZNF100; TH1L; ELAC2; SSRP1
tRNA processing
TRMT44; TRMT12; CCDC76; CDKAL1; C22orf28; METTL1; ZBTB8OS; C2orf49; TSEN54; TSEN2
tRNA processing in the nucleus
TSEN54; RPP38; TSEN34; XPOT; POP4; RPP14; C22orf28; TSEN15; FAM98B; ZBTB8OS

Protein Function

TSEN54 has several biochemical functions, for example, protein binding, contributes_to tRNA-intron endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TSEN54 itself. We selected most functions TSEN54 had, and list some proteins which have the same functions with TSEN54. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein GLRX3; ZNF622; CD79A; HIST3H3; KRTAP10-9; SCRN1; RUFY1; IL17RA; ZFYVE28; MUTYH
Function contributes_to tRNA-intron endonuclease activity
Related Protein TSEN54

Interacting Protein

TSEN54 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSEN54 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSEN54.
TSEN2; Clp1; CSNK2B

TSEN54 Related Articles

Bierhals, T; Korenke, GC; et al. Pontocerebellar hypoplasia type 2 and TSEN2: Review of the literature and two novel mutations. EUROPEAN JOURNAL OF MEDICAL GENETICS 56:325-330(2013).
Namavar, Y; Chitayat, D; et al. TSEN54 mutations cause pontocerebellar hypoplasia type 5. EUROPEAN JOURNAL OF HUMAN GENETICS 19:724-726(2011).