tuba4a
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  • Official Full Name
  • tubulin, alpha 4a
  • Background
  • Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin.
  • Synonyms
  • TUBA4A; tubulin, alpha 4a; TUBA1, tubulin, alpha 1 , tubulin, alpha 1 (testis specific); tubulin alpha-4A chain; FLJ30169; H2 ALPHA; tubulin H2-alpha; tubulin alpha-1 chain; tubulin, alpha 1 (testis specific); TUBA1; H2-ALPHA
Cat.#:TUBA4A-17613MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TUBA4A Protein
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Cat.#:TUBA4A-6359RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TUBA4A Protein
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Cat.#:TUBA4A-656HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TUBA4A 293 Cell Lysate
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Involved Pathway

TUBA4A involved in several pathways and played different roles in them. We selected most pathways TUBA4A participated on our site, such as Phagosome, Gap junction, Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBA4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phagosome
SEC61AL2; HLA-DRB3; ATP6V0A2; ITGB1B.2; SEC61G; HLA-DRB1; HLA-G; HLA-E; FCGR3A; TUBB2A
Gap junction
DRD2L; TUBA3C; GNAS; TUBA8L; GRM1; GNA15.1; GRB2A; TUBA8; HRASA; TUBA1L
Pathogenic Escherichia coli infection
KRT18; TUBB2B; TUBB6; YWHAZ; TLR5; TLR4; OCLN; ARPC5L; CD14; ARHGEF2

Protein Function

TUBA4A has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBA4A itself. We selected most functions TUBA4A had, and list some proteins which have the same functions with TUBA4A. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein SEPT12; ACSM1; ASCL1B; RAB5C; ERCC3; ADSSL1; ARL8; RAP2A; TUFM; SEPT5B
Function GTPase activity
Related Protein GNAV1; GBP2; TUBB2A; RAB35; GNAI2; RHOT2; EIF2S3; RAB1A; EFTUD1; RRAGB
Function protein binding
Related Protein FEM1C; DGKZ; TP53RK; SPG11; UBE2D2; ACSS1; ABCE1; CNST; KLK15; MYLIP
Function structural constituent of cytoskeleton
Related Protein ACTR3; TUBB2A; ACTG1; TUBB6; NDC80; TUBGCP5; NEFL; KRT6B; MAPT; ATXN1

Interacting Protein

TUBA4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBA4A here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBA4A.
CLIP1; EGFR; MYC; E2F1; SMAD2; SMAD1; STARD13; GNAI2; S100A8; ENO2; RPL12; TM4SF1; ACTN2