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TUBA4A

Official Full Name

tubulin, alpha 4a
Overview

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin.
Synonyms

TUBA4A; tubulin, alpha 4a; TUBA1, tubulin, alpha 1 , tubulin, alpha 1 (testis specific); tubulin alpha-4A chain; FLJ30169; H2 ALPHA; tubulin H2-alpha; tubulin alpha-1 chain; tubulin, alpha 1 (testis specific); TUBA1; H2-ALPHA;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TUBA4A-656HCL	Recombinant Human TUBA4A 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	TUBA4A-17613M	Recombinant Mouse TUBA4A Protein	Mammalian Cell	His	Inquiry
Mouse	TUBA4A-9757M-B	Recombinant Mouse TUBA4A Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	TUBA4A-9757M	Recombinant Mouse TUBA4A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	TUBA4A-6359R	Recombinant Rat TUBA4A Protein	Mammalian Cell	His	Inquiry
Rat	TUBA4A-6015R	Recombinant Rat TUBA4A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	TUBA4A-6015R-B	Recombinant Rat TUBA4A Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

TUBA4A involved in several pathways and played different roles in them. We selected most pathways TUBA4A participated on our site, such as Phagosome, Gap junction, Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBA4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Phagosome	TUBA4A;ATP6V1G2;ATP6V1E2;MRC2;EEA1;TUBA3C;VAMP3;ATP6AP1;FCGR3
Gap junction	PRKACBB;PRKACB;GNA15.1;TUBA4A;TUBA2;TUBA8L2;HRASB;PRKACBA;PRKCB
Pathogenic Escherichia coli infection	TUBA1B;ACTG1;RHOA;CDC42;FYN;ARHGEF2;ITGB1;TUBA1C;NCK1

TUBA4A has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBA4A itself. We selected most functions TUBA4A had, and list some proteins which have the same functions with TUBA4A. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	ARL14;RAB42B;RASL10B;HRASA;RHOUA;TUBAL3;RRAGCB;RAB26;RAB34A
GTPase activity	RAB14L;RAB41;ATL1;RAB27B;RABL5;SAR1B;RAB3DB;MXG;RRAS
protein binding	EHD2;MAGEH1;ZMYM4;BID;SNX9;TUBB2A;AKR1B10;GTF2H2C;GPR37L1
structural constituent of cytoskeleton	ACTG1;ATXN1;KRT17;NEFH;TUBA4L;ACTL7A;SPTA1;MSN;ACTL7B

TUBA4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBA4A here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBA4A.

CLIP1; EGFR; MYC; E2F1; SMAD2; SMAD1; STARD13; GNAI2; S100A8; ENO2; RPL12; TM4SF1; ACTN2