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TUBB1

  • Official Full Name

    tubulin, beta 1 class VI

  • Overview

    This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
  • Synonyms

    TUBB1; tubulin, beta 1 class VI; tubulin, beta 1; tubulin beta-1 chain; class VI beta tubulin; dJ543J19.4; M(beta)1; 2810484G07Rik; Beta tubulin 1, class VI; class VI beta-tubulin;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat germ
  • GST
  • His
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TUBB1-1303H Recombinant Human TUBB1 protein, His & T7-tagged E.coli His/T7 Ser166~His451 (Accession # Q9H4B7)
Human TUBB1-652HCL Recombinant Human TUBB1 293 Cell Lysate HEK293 N/A
Human TUBB1-6776HF Recombinant Full Length Human TUBB1 Protein, GST-tagged In Vitro Cell Free System GST 451 amino acids
Human TUBB1-03H Recombinant Human TUBB1 Protein, GST-tagged Wheat germ GST
Human TUBB1-6610H Recombinant Human TUBB1 Protein (Ser166-His451), N-His tagged E.coli N-His Ser166-His451
Human TUBB1-6609H Recombinant Human TUBB1 Protein (Ser166-His452), His tagged E.coli His Ser166-His452
Mouse Tubb1-1304M Recombinant Mouse Tubb1 protein, His & T7-tagged E.coli His/T7 Pro182~Glu437 (Accession # A2AQ07)
Chicken TUBB1-6995C Recombinant Chicken TUBB1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TUBB1 involved in several pathways and played different roles in them. We selected most pathways TUBB1 participated on our site, such as Phagosome, Gap junction, Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PhagosomeTUBA3A;TLR4BA;PIK3C3;FCAR;TAP2;CTSSB.2;TUBA8L3;ATP6V1B1;HLA-G
Gap junctionPRKCB;PRKCBA;TUBB6;NRAS;GUCY1A3;GNAI3;GNA11;HTR2A;GJA1
Pathogenic Escherichia coli infectionTUBA1B;WAS;TUBAL3;TUBA3C;TUBA3E;CLDN1;TUBB7P;RHOA;ROCK1

TUBB1 has several biochemical functions, for example, GTP binding, GTPase activity, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBB1 itself. We selected most functions TUBB1 had, and list some proteins which have the same functions with TUBB1. You can find most of the proteins on our site.

Function Related Protein
GTP bindingRAB34A;TUBA1B;RHEBL1;ARF4B;HHAT;TUBA8L2;SEPT7A;SEPT10;GIMAP3
GTPase activityRAB38;GNAI1;RABL2A;RAB14L;RAB3DA;RAB42;RAB1B;RAB30;TUBB4B
structural constituent of cytoskeletonDES;TUBB6;TUBE1;SPTBN2;TUBA3E;ACTR2;CTNNA2;ATXN1;ARPC3

TUBB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBB1.

SNW1; a8k1f4_human; DYNC1I1; MLF1; YWHAZ; PSMD2; CDC37; Hacd3; q96be0_human; AARSD1; LRRK2; 15-deoxy-delta(12,14; ere_dna; Psmd14; GABARAP; HTR7; GABARAPL2; MDM2; STK4

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