tubb1
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  • Official Full Name
  • tubulin, beta 1 class VI
  • Background
  • This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
  • Synonyms
  • TUBB1; tubulin, beta 1 class VI; tubulin, beta 1; tubulin beta-1 chain; class VI beta tubulin; dJ543J19.4; M(beta)1; 2810484G07Rik; Beta tubulin 1, class VI; class VI beta-tubulin
Cat.#:TUBB1-03HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human TUBB1 Protein, GST-tagged
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Cat.#:TUBB1-1303HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TUBB1 protein, His & T7-tagged
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Cat.#:Tubb1-1304MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Tubb1 protein, His & T7-tagged
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Cat.#:TUBB1-6995CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TUBB1
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Cat.#:TUBB1-652HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TUBB1 293 Cell Lysate
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Involved Pathway

TUBB1 involved in several pathways and played different roles in them. We selected most pathways TUBB1 participated on our site, such as Phagosome, Gap junction, Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phagosome
MPO; HLA-DRA; C1RA; ATP6V1E2; MARCO; HLA-DRB5; TUBA8L2; BLB1; TUBA2; STX7
Gap junction
PLCB1; TUBA8L4; CSNK1DA; PLCB3; PDGFAA; PRKACBA; TUBA1A; GNA11; RAF1A; PRKCBB
Pathogenic Escherichia coli infection
TUBA3E; ARPC5L; TUBAL3; TUBB7P; CDC42; WASL; TUBB1; NCK2; TLR5; ABL1

Protein Function

TUBB1 has several biochemical functions, for example, GTP binding, GTPase activity, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBB1 itself. We selected most functions TUBB1 had, and list some proteins which have the same functions with TUBB1. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein RAP1AB; RAB6B; EEF1A2; CDC42; RAB25A; GFM1; NKIRAS2; MFN2; RAB8B; MTIF2
Function GTPase activity
Related Protein LRRK2; RAB20; RAB4B; HRAS; TUBA4L; DNM2; ARHGAP5; RASEF; RHOU; GNA13B
Function structural constituent of cytoskeleton
Related Protein NDC80; TUBA8L2; TUBGCP2; TUBB6; KRT6B; TUBA1L; VIM; SPTAN1; ANK1; TLN2A

Interacting Protein

TUBB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBB1.
SNW1; a8k1f4_human; DYNC1I1; MLF1; YWHAZ; PSMD2; CDC37; Hacd3; q96be0_human; AARSD1; LRRK2; 15-deoxy-delta(12,14; ere_dna; Psmd14; GABARAP; HTR7; GABARAPL2; MDM2; STK4