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TYW3

  • Official Full Name

    tRNA-yW synthesizing protein 3 homolog

  • Overview

    Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).
  • Synonyms

    TYW3; tRNA-yW synthesizing protein 3 homolog (S. cerevisiae); C1orf171, chromosome 1 open reading frame 171; tRNA wybutosine-synthesizing protein 3 homolog; FLJ40918; tRNA-yW-synthesizing protein 3; C1orf171;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TYW3-611HCL Recombinant Human TYW3 293 Cell Lysate HEK293 N/A
Human TYW3-1881H Recombinant Human TYW3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Tyw3-6761M Recombinant Mouse Tyw3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque TYW3-5045R Recombinant Rhesus monkey TYW3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TYW3-4858R-B Recombinant Rhesus Macaque TYW3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TYW3-4858R Recombinant Rhesus Macaque TYW3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TYW3-725Z Recombinant Zebrafish TYW3 Mammalian Cell His
Chicken TYW3-5014C Recombinant Chicken TYW3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TYW3 involved in several pathways and played different roles in them. We selected most pathways TYW3 participated on our site, such as 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis, Gene Expression, Synthesis of wybutosine at G37 of tRNA(Phe), which may be useful for your reference. Also, other proteins which involved in the same pathway with TYW3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
7-(3-amino-3-carboxypropyl)-wyosine biosynthesisTYW1;TYW3
Gene ExpressionZNF550;ZNF468;JUNB;EED;ZNF554;ZNF324;ZNF257;ZNF691;SAP30BP
Synthesis of wybutosine at G37 of tRNA(Phe)TRMT5;TRMT12;TYW3;TYW5;TYW1;LCMT2
tRNA modification in the nucleus and cytosolOSGEP;LCMT2;METTL1;TYW5;TYW3;WDR4;ALKBH8;TRMT11;TRDMT1
tRNA processingTHG1L;TRDMT1;TYW3;CCDC76;TRMT44;TRMT5;ELAC2;TRMT1;TYW1
wybutosine biosynthesisLCMT2;TYW3;TYW1

TYW3 has several biochemical functions, for example, methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TYW3 itself. We selected most functions TYW3 had, and list some proteins which have the same functions with TYW3. You can find most of the proteins on our site.

Function Related Protein
methyltransferase activityPRMT1;SETD1BA;COMTB;FAM86C;NTMT1;METTL21A;ASMT2;EHMT1;PRMT5

TYW3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TYW3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TYW3.

ZWINT; Smchd1; Mis12

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