UBA5 Protein, ubiquitin-like modifier activating enzyme 5


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Official Full Name ubiquitin-like modifier activating enzyme 5
Background This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A pseudogene located on chromosome 1 has also been identified.
Synonyms UBA5; ubiquitin-like modifier activating enzyme 5; UBE1DC1, ubiquitin activating enzyme E1 domain containing 1; ubiquitin-like modifier-activating enzyme 5; FLJ23251; ubiquitin activating enzyme E1 homolog (yeast); 5730525G14Rik; AW240750; FLJ23251UBA5; MGC105565; THIFP1; UBA5 ubiquitin activating enzyme E1 homolog; UBE1DC1; Ubiquitin activating enzyme 5; Ubiquitin activating enzyme E1 domain containing protein 1; Ubiquitin like modifier activating enzyme 5; UFM1 activating enzyme; UFM1-activating enzyme; ubiquitin-activating enzyme 5; UBA5, ubiquitin-activating enzyme E1 homolog; ubiquitin-activating enzyme E1-domain containing 1; ubiquitin-activating enzyme E1 domain-containing protein 1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBA5-15847H Recombinant Human UBA5, His-tagged E.coli His
    Human UBA5-1958H Recombinant Human Ubiquitin-Like Modifier Activating Enzyme 5, His-tagged E.coli His
    Human UBA5-2143HCL Recombinant Human UBA5 cell lysate N/A
    Human UBA5-3516H Recombinant Human UBA5, GST-tagged E.coli GST
    Mouse UBA5-17690M Recombinant Mouse UBA5 Protein Mammalian Cell His
    Rat UBA5-6387R Recombinant Rat UBA5 Protein Mammalian Cell His
    Chicken UBA5-1160C Recombinant Chicken UBA5 Mammalian Cell His

    UBA5 involved in several pathways and played different roles in them. We selected most pathways UBA5 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System LILRB2; SPSB1; CXADR; ITK; TRIM9; RNF220; ICAM4; LILRB4; FBXO44; NRG2A
    Antigen processing: Ubiquitination &amp UBR2; TRIM69; WSB1; DTX3L; ASB13; UBE2V2; TRAF7; LRR1; ASB14; ASB6
    Proteasome degradation RNF138; KLHL21; RNF123; ASB11; RNF25; RNF19B; TRIM41; HECTD3; FBXO27; STUB1
    Class I MHC mediated antigen processing &amp RNF34; LRSAM1; TRIM9; UBE2F; ASB14; FBXO27; VPRBP; TPP2; ASB8; PJA2
    presentation STUB1; LRRC41; LRR1; RNF220; TRIM63; UBE2J2; UBE2V2; UBE2L6; FBXO17; RNF41
    Immune System DDX41; KIF22; DEFA6; IRF6; LRRFIP1; POLR3F; CD200R2; IFIT3; AP1G1; KIF20A
    protein ubiquitylation UEVLD; UBA5; UBE2U; RNF216; UBE2E3

    UBA5 has several biochemical functions, for example, ATP binding, UFM1 activating enzyme activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBA5 itself. We selected most functions UBA5 had, and list some proteins which have the same functions with UBA5. You can find most of the proteins on our site.

    Function Related Protein
    UFM1 activating enzyme activity UBA5
    metal ion binding SP8A; PRKAA2; GALNTL1; TESK1; PLA2G4F; DMRT2; ZEB2; RPE65B; ZNF398; THOP1
    protein binding OTULIN; TAF9B; TXNRD2; ADRA2C; Ntng2; ESRP1; CSGALNACT2; AURKB; PER3; NSMCE2

    UBA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBA5.


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