UBE2G1 Protein, ubiquitin-conjugating enzyme E2G 1

UBE2G1

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UBE2G1

Official Full Name ubiquitin-conjugating enzyme E2G 1
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived;proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or;E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the;E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The;protein may be involved in degradation of muscle-specific proteins.
Synonyms UBE2G1; ubiquitin-conjugating enzyme E2G 1; UBE2G, ubiquitin conjugating enzyme E2G 1 (homologous to C. elegans UBC7) , ubiquitin conjugating enzyme E2G 1 (UBC7 homolog, C. elegans) , ubiquitin conjugating enzyme E2G 1 (UBC7 homolog, yeast); ubiquitin-
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBE2G1-09H Recombinant Human Ubiquitin Conjugating Enzyme 7 E.coli N/A
    Human UBE2G1-267H Recombinant Human UBE2G1, His-tagged E.coli His
    Human UBE2G1-3534H Recombinant Human UBE2G1, GST-tagged E.coli GST
    Human UBE2G1-579HCL Recombinant Human UBE2G1 293 Cell Lysate HEK293 N/A
    Human UBE2G1-648H Recombinant Human UBE2G1 Protein, His-tagged, Active E.coli His
    Human UBE2G1-667H Recombinant Human ubiquitin-conjugating enzyme E2G 1, His-tagged E.coli His
    Human UBE2G1-854H Recombinant Human UBE2G1, None tagged E.coli N/A
    Mouse UBE2G1-17716M Recombinant Mouse UBE2G1 Protein Mammalian Cell His
    Rat UBE2G1-6400R Recombinant Rat UBE2G1 Protein Mammalian Cell His
    Cynomolgus Monkey UBE2G1-1074C Recombinant Cynomolgus UBE2G1 Protein, His-tagged Mammalian Cell His
    Chicken UBE2G1-3638C Recombinant Chicken UBE2G1 Mammalian Cell His

    UBE2G1 involved in several pathways and played different roles in them. We selected most pathways UBE2G1 participated on our site, such as Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2G1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis PIAS2; RHOBTB2; SKP2; UBE2L3; PIAS1; UBE2KB; RHOBTB2A; TCEB2; NEDD4; UBE2R2
    Protein processing in endoplasmic reticulum HSC70; BAXA; FBXO6; CRYAB; BAG2; DNAJB1A; HYOU1; CAPN2; SEC63; MARCH6
    Parkinsons disease ATP5D; PARK7; UQCR10; COX6B2; NDUFV2; NDUFB11; NDUFS6; PRKACG; NDUFB2; NDUFA6

    UBE2G1 has several biochemical functions, for example, ATP binding, ubiquitin conjugating enzyme activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2G1 itself. We selected most functions UBE2G1 had, and list some proteins which have the same functions with UBE2G1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding DNAJA3; MKKS; MOK; ABL2; PRKCBA; CDKL1; MTHFD1; CDK9; SBK3; CDKL2
    ubiquitin conjugating enzyme activity UBE2L3; CDC34; UBE2Z; UBE2H; UBE2O; UBE2V2; UBE2R2; UBE2D2A; UBE2D4; UBE2QL1
    ubiquitin protein ligase activity RNF111; TRIM6; RNF144A; FBXL22; HLTF; UBE2R2; RABGEF1; RNF24; HECTD1; ZSWIM2
    ubiquitin protein ligase binding UBE2N; AICDA; UBE2V2; GGN; UBE2V1; NDUFS2; H2-AB1; IKBKG; ABI2; RANGAP1
    ubiquitin-protein transferase activity MDM2; MARCH5L; TRAF4A; TRIM32; TRAF4B; TRIP12; MALT1; TRIM37; RNF10; RFWD3

    UBE2G1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2G1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2G1.

    CUL1; RBCK1; Tmed10

    Choi, YS; Lee, YJ; et al. Differential Ubiquitin Binding by the Acidic Loops of Ube2g1 and Ube2r1 Enzymes Distinguishes Their Lys-48-ubiquitylation Activities. JOURNAL OF BIOLOGICAL CHEMISTRY 290:2251-2263(2015).
    Evangelou, M; Smyth, DJ; et al. A Method for Gene-Based Pathway Analysis Using Genomewide Association Study Summary Statistics Reveals Nine New Type 1 Diabetes Associations. GENETIC EPIDEMIOLOGY 38:661-670(2014).

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