UBE2N Protein, ubiquitin-conjugating enzyme E2N

UBE2N

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UBE2N

Official Full Name ubiquitin-conjugating enzyme E2N
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived;proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or;E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the;E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication;repair.
Synonyms UBE2N; ubiquitin-conjugating enzyme E2N; ubiquitin conjugating enzyme E2N (homologous to yeast UBC13) , ubiquitin conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-conjugating enzyme E2 N; MGC8489; UBC13; UbcH ben; yeast UBC13 homolog; ubiquitin-p
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBE2N-136H Recombinant Human UBE2N E.coli N/A
    Human UBE2N-238H Recombinant Human UBE2N, His-tagged E.coli His
    Human UBE2N-3540H Recombinant Human UBE2N, GST-tagged E.coli GST
    Human UBE2N-566HCL Recombinant Human UBE2N 293 Cell Lysate HEK293 N/A
    Human UBE2N-62H Recombinant Human UBE2N, His-tagged E.coli His
    Human UBE2N-650H Recombinant Human UBE2N Protein, His-tagged, Active E.coli His
    Rat UBE2N-6403R Recombinant Rat UBE2N Protein Mammalian Cell His
    Cynomolgus Monkey UBE2N-1075C Recombinant Cynomolgus UBE2N Protein, His-tagged Mammalian Cell His
    Rhesus Macaque UBE2N-5066R Recombinant Rhesus monkey UBE2N Protein, His-tagged Mammalian Cell His
    Chicken UBE2N-2038C Recombinant Chicken UBE2N Mammalian Cell His

    UBE2N involved in several pathways and played different roles in them. We selected most pathways UBE2N participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2N were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis SAE1; UBE2D1B; ANAPC4; SKP1; UBA3; ANAPC2; RFWD2; MAP3K1; RNF7; RBX1

    UBE2N has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2N itself. We selected most functions UBE2N had, and list some proteins which have the same functions with UBE2N. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding NAGK; ERBB3B; PLK2; PMVK; PHKG1B; ABCA4A; MAPK14B; UCKL1A; JAK2A; ACVRL1
    poly(A) RNA binding TRIM56; UTP11L; HEATR6; HIST1H1C; HSPA9; DDX39A; CFAP20; HNRNPL; CEBPZ; YWHAE
    protein binding DNAJB1; DEDD; SUSD2; SCARF1; WAPAL; MPDU1; S100B; IGFBP7; ALOX12B; ZFYVE9
    ubiquitin binding DYRK2; CXCR4; RBCK1; DNAJC2; TSG101; UBAP1; NPLOC4; USP16; C6orf106; KCNS1
    ubiquitin conjugating enzyme activity UBE2Q2; UBE2C; UBE2E3; UBE2T; UBE2A; UBE2N; UBE2G1; UBE2L3; UBE2D3; UBE2QL1
    ubiquitin protein ligase activity PPIL2; RNF220; UBR2; RNF144AB; RNF180; MED10; CBLC; BFAR; STUB1; MED7
    ubiquitin protein ligase binding CCT2; GPI1; CUL4B; HSPA1B; PRDX6; CKB; CUL3; TXNIP; UBE2L3; PER1
    ubiquitin-protein transferase activity FBXO40.1; ITCH; UHRF1; MARCH2; CNOT4B; UBE2H; TRAF6; UBE2M; TRIM71; TRAF4

    UBE2N has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2N here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2N.

    UBE2V1; STUB1

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