ube2n
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  • Official Full Name
  • ubiquitin-conjugating enzyme E2N
  • Background
  • The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived;proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or;E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the;E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication;repair.
  • Synonyms
  • UBE2N; ubiquitin-conjugating enzyme E2N; ubiquitin conjugating enzyme E2N (homologous to yeast UBC13) , ubiquitin conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-conjugating enzyme E2 N; MGC8489; UBC13; UbcH ben; yeast UBC13 homolog; ubiquitin-p
Cat.#:UBE2N-62HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UBE2N, His-tagged
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Cat.#:UBE2N-136HTag:
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human UBE2N
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Cat.#:UBE2N-238HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UBE2N, His-tagged
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Cat.#:UBE2N-3540HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UBE2N, GST-tagged
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Cat.#:UBE2N-650HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UBE2N Protein, His-tagged, Active
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Cat.#:UBE2N-6403RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UBE2N Protein
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Cat.#:UBE2N-1075CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus UBE2N Protein, His-tagged
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Cat.#:UBE2N-5066RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey UBE2N Protein, His-tagged
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Cat.#:UBE2N-2038CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken UBE2N
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Cat.#:UBE2N-566HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human UBE2N 293 Cell Lysate
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Involved Pathway

UBE2N involved in several pathways and played different roles in them. We selected most pathways UBE2N participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2N were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ubiquitin mediated proteolysis
FBXW11A; PIAS1; VHL; MID1; UBE2D4; MDM2; TCEB1B; UBE2E1; TCEB1; SKP2

Protein Function

UBE2N has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2N itself. We selected most functions UBE2N had, and list some proteins which have the same functions with UBE2N. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PIKFYVE; SYN2A; TAF1; ACVR1L; RTCD1; ADCY9; HLTF; HSPH1; ITPKB; STK36
Function poly(A) RNA binding
Related Protein RPS6; SUMO1; RBM12B; DDX49; LBR; NMD3; SNRPG; DMGDH; RBM26; EIF3E
Function protein binding
Related Protein KRTAP19-7; TBC1D23; CXXC11; AXIN1; CUTC; AXIN2; PRDM4; RASA1; TNFRSF1B; C11orf65
Function ubiquitin binding
Related Protein IDE; D17WSU92E; KCNS1; OTUB1; FAN1; CXCR4; FAF2; C6orf106; USP16; SQSTM1
Function ubiquitin conjugating enzyme activity
Related Protein UBE2G2; UBE2V2; UBE2D3; UBE2R2; UBE2N; UBE2V1; UBE2A; UBE2D2; UBE2S; UBE2O
Function ubiquitin protein ligase activity
Related Protein WWP1; LRSAM1; CCNC; ANKIB1A; ASB4; RNF146; MDM2; PDZRN4; ZNRF1; TRIM3
Function ubiquitin protein ligase binding
Related Protein ACVR1B; AXIN2; FLJ11011L; CKB; BECN1; FAF2; GPR37; YWHAE; VCL; UBE2R2
Function ubiquitin-protein transferase activity
Related Protein RNF4; RNF217; UBE2T; UBE2C; RNF125; ZFP91; ZER1; TRIM2; TRIM37; UBE2H

Interacting Protein

UBE2N has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2N here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2N.
UBE2V1; STUB1