|Official Full Name||ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase|
|Background||This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis.|
|Synonyms||UHRF2; ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase; ubiquitin like with PHD and ring finger domains 2; E3 ubiquitin-protein ligase UHRF2; MGC33463; NIRF; Np95 like ring finger protein; RNF107; URF2; nuclear protein 97; R|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
UHRF2 involved in several pathways and played different roles in them. We selected most pathways UHRF2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with UHRF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
UHRF2 has several biochemical functions, for example, DNA binding, histone binding, ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UHRF2 itself. We selected most functions UHRF2 had, and list some proteins which have the same functions with UHRF2. You can find most of the proteins on our site.
|DNA binding||GTF2E2; ISX; BARX2; BHLHE41; CHD1; POLR2C; ZNF705A; ZNF791; MYO18A; NKX2.7|
|histone binding||PKN1; NPM2; ATRX; NCAPD3; APBB1; HIST1H3C; TBL1XR1; HIST1H47; NAP1L2; CD1d1|
|ligase activity||TRIM8; CPS1; RNF115; TRIM68; UBE2L3B; TTLL5; DTX3; SH3RF2; RNF170; MYLIPA|
|protein binding||NUP54; OFD1; C7orf53; HMGN2; SEPT1; MAPK10; F2R; FAM81B; PEX26; COG1|
|ubiquitin protein ligase activity||UBE2KA; RNF34; COP1; FBXO6; RNF175; TRAF6; TRIP12; RNF121; FBXO30; UBE2S|
|ubiquitin-protein transferase activity||DTX3L; BARD1; RNF115; FBXO7; UBE2N; MARCH5; MARCH8; MUL1; CNOT4; RNF144B|
|zinc ion binding||UNKL; EWSR1A; AGBL2; PPARAB; LHX1B; FBXO11A; APOBEC1; LIMA1; TRIM54; ZCCHC7|
UHRF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UHRF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UHRF2.
CDK2; CCND1; CCNE1; RB1; TP53