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USH2A

Official Full Name

Usher syndrome 2A (autosomal recessive, mild)
Overview

This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

USH2A; Usher syndrome 2A (autosomal recessive, mild); USH2; usherin; RP39; dJ1111A8.1; US2; Usher syndrome type IIa protein; Usher syndrome type-2A protein; OTTHUMP00000035145; OTTHUMP00000063383;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Mouse
Rat

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	USH2A-17894M	Recombinant Mouse USH2A Protein	Mammalian Cell	His	Inquiry
Mouse	USH2A-9942M	Recombinant Mouse USH2A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	USH2A-9942M-B	Recombinant Mouse USH2A Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	USH2A-6464R	Recombinant Rat USH2A Protein	Mammalian Cell	His	Inquiry
Rat	USH2A-6120R	Recombinant Rat USH2A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	USH2A-6120R-B	Recombinant Rat USH2A Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

USH2A involved in several pathways and played different roles in them. We selected most pathways USH2A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with USH2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

USH2A has several biochemical functions, for example, collagen binding, myosin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USH2A itself. We selected most functions USH2A had, and list some proteins which have the same functions with USH2A. You can find most of the proteins on our site.

Function	Related Protein
collagen binding	PODN;GPR56;LUM;C1QTNF1;ITGA1;SERPINH2;Pdgfa&Pdgfb;ITGA3;CTSL1
myosin binding	ARFGEF1;ACTA1;FXYD1;NPHS1;USH2A;ARFGEF2;VAMP2;CALD1B;KIRREL
protein binding	NAT9;ZHX3;TXNRD2;SPPL2B;CD79A;ATE1;AEBP2;THOC5;FNDC3B
protein homodimerization activity	COMMD1;CARM1;BCL2L10;GALE;KIAA1804;CEP57;APOA4;IMPA2;MSH2

USH2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USH2A here. Most of them are supplied by our site. Hope this information will be useful for your research of USH2A.