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USP9X

Official Full Name

ubiquitin specific peptidase 9, X-linked
Overview

This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Synonyms

USP9X; ubiquitin specific peptidase 9, X-linked; FAF; FAM; DFFRX; probable ubiquitin carboxyl-terminal hydrolase FAF-X; hFAM; fat facets in mammals; ubiquitin thioesterase FAF-X; deubiquitinating enzyme FAF-X; ubiquitin thiolesterase FAF-X; fat facets protein related, X-linked; fat facets protein-related, X-linked; Drosophila fat facets related, X-linked; ubiquitin-specific protease 9, X chromosome; ubiquitin-specific processing protease FAF-X; ubiquitin-specific-processing protease FAF-X; ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila);

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
Mammalian Cell
Sf21 Insect Cell

Tag

GST
His
His (Fc)
Avi
Met|His
No tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	USP9X-184H	Active Recombinant Human USP9X, GST-tagged	E.coli	GST		Inquiry
Human	USP9X-658H	Active Recombinant Human USP9X, Met&His-tagged	Sf21 Insect Cell	Met/His		Inquiry
Human	USP9X-0343H	Recombinant Human USP9X Protein (K1554-N1995), GST tagged	E.coli	GST	K1554-N1995	Inquiry
Human	USP9X-0344H	Recombinant Human USP9X Protein (K1554-N1995), Tag Free	E.coli	No tag	K1554-N1995	Inquiry
Mouse	USP9X-17945M	Recombinant Mouse USP9X Protein	Mammalian Cell	His		Inquiry
Mouse	USP9X-9977M	Recombinant Mouse USP9X Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	USP9X-9977M-B	Recombinant Mouse USP9X Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
USP9X Related Research Area

USP9X involved in several pathways and played different roles in them. We selected most pathways USP9X participated on our site, such as Downregulation of SMAD2/3:SMAD4 transcriptional activity, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP9X were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Downregulation of SMAD2/3:SMAD4 transcriptional activity	RNF111;SKIB;SKI;SKILB;USP9;TRIM33;USP9X;SMAD3B;PARP1
Gene Expression	LSM11;ZNF530;AIMP1;HENMT1;DDX4;SKIB;ZNF445;NR1D2B;ZNF664
Generic Transcription Pathway	ZNF266;ZNF180;ZNF354A;ZNF747;ZNF43;ZNF460;ZNF433;ZNF710;ZNF256
Signal Transduction	TAC1;EMR4;MKL1B;NMT1A;DEPDC7;FGFBP1;APOA4B.2;RGS6;NMU
Signaling by TGF-beta Receptor Complex	SKILB;SKIA;USP9X;PMEPA1;NEDD8;SKIB;STRAP;CGNB;NEDD8L
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	SKILB;SKIB;USP9X;TRIM33;USP9

USP9X has several biochemical functions, for example, co-SMAD binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP9X itself. We selected most functions USP9X had, and list some proteins which have the same functions with USP9X. You can find most of the proteins on our site.

Function	Related Protein
co-SMAD binding	GATA4;TRIM33;SMAD1;CITED1;TGIF1;FOXH1;SMAD3;SMAD6;USP9X
cysteine-type endopeptidase activity	ATG4C;CTSL.1;ATG4B;USP17L5;CASP8L1;USP49;MALT1A;CTSZ;USP34
cysteine-type peptidase activity	CTSLA;ZRANB1B;CTS7;CASP3A;USP9;OTUD7A;UFSP2;ALG13;CAPN1B
protein binding	CD70;LBH;MYO6;DNAJB4;ATXN10;ARSI;FGD5;TMEM31;YARS2
ubiquitin-specific protease activity	EIF3F;USP1;OTUB2;USP18;USP45;USP2A;USP7;OTUD4;OTUD7B

USP9X has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP9X here. Most of them are supplied by our site. Hope this information will be useful for your research of USP9X.

NFKB2; NUAK1; MYC; JUN; PHB; CASP4; NFKB2; RELB; MAP3K1; SMAD4; TSC22D1; NEK6; HTT

Deubiquitinating Enzymes (DUBs)