vps37c
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  • Official Full Name
  • vacuolar protein sorting 37 homolog C (S. cerevisiae)
  • Background
  • VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar;protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of;multivesicular bodies (Eastman et al., 2005 (PubMed 15509564)).
  • Synonyms
  • VPS37C; vacuolar protein sorting 37 homolog C (S. cerevisiae); vacuolar protein sorting 37C (yeast); vacuolar protein sorting-associated protein 37C; FLJ20847; 5730409F24Rik; AU042646; ESCRT I complex subunit VPS37C; ESCRT-I complex subunit VPS37C; hVps37C; PML39; RGD1309258; Vacuolar protein sorting 37C; Vacuolar protein sorting associated protein 37C; VP37C_HUMAN; OTTHUMP00000236974; OTTHUMP00000236975
Cat.#:VPS37C-18376MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse VPS37C Protein
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Cat.#:VPS37C-4393CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken VPS37C
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Cat.#:VPS37C-4861ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish VPS37C
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Involved Pathway

VPS37C involved in several pathways and played different roles in them. We selected most pathways VPS37C participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS37C were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endocytosis
CAV3; RAB31; DNM3; CDC42; ARPC4L; RAB11BB; PRKCZ; CYTH3; ARAP3; CAPZA1

Protein Function

VPS37C has several biochemical functions, for example, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS37C itself. We selected most functions VPS37C had, and list some proteins which have the same functions with VPS37C. You can find most of the proteins on our site.
Function
Related Protein
Function calcium-dependent protein binding
Related Protein MBL2; MASP2; S100A6; DDX5; ANXA7; CPNE3; STX1A; CALM2; PDCD6; VPS37B

Interacting Protein

VPS37C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS37C here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS37C.
Dock1

VPS37C Related Articles

Okumura, M; Katsuyama, AM; et al. VPS37 Isoforms Differentially Modulate the Ternary Complex Formation of ALIX, ALG-2, and ESCRT-I. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 77:1715-1721(2013).
Stefani, F; Zhang, L; et al. UBAP1 Is a Component of an Endosome-Specific ESCRT-I Complex that Is Essential for MVB Sorting. CURRENT BIOLOGY 21:1245-1250(2011).