wdr19
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  • Official Full Name
  • WD repeat domain 19
  • Background
  • This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains six WD repeats, a clathrin heavy-chain repeat, and three transmembrane domains. This gene is conserved from C. elegans to human. It may participate in androgen-regulated signaling mechanisms or in the vesicular trafficking of androgen-regulated secretory processes. Alternatively spliced transcript variants encoding distinct isoforms have been reported but the full-length nature of one of these variants has not been defined.
  • Synonyms
  • WDR19; WD repeat domain 19; WD repeat-containing protein 19; DYF 2; FLJ23127; IFT144; intraflagellar transport 144 homolog (Chlamydomonas); KIAA1638; ORF26; Oseg6; Pwdmp; DYF2; Intraflagellar transport 144 homolog; WD repeat containing protein 19; WD repeat membrane protein PWDMP; WDR19_HUMAN; OTTHUMP00000218257; DYF-2
Cat.#:WDR19-3709HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human WDR19, His-tagged
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Cat.#:WDR19-18456MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse WDR19 Protein
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Cat.#:WDR19-5194RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey WDR19 Protein, His-tagged
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Cat.#:WDR19-1925HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human WDR19 cell lysate
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Involved Pathway

WDR19 involved in several pathways and played different roles in them. We selected most pathways WDR19 participated on our site, such as Assembly of the primary cilium, Hedgehog off state, Intraflagellar transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Assembly of the primary cilium
MAPRE1B; WDR19; DYNC1H1; CCT8; CEP63; CEP78; IFT22; CSNK1E; BBS7; TRIP11
Hedgehog off state
BBS13; TULP3; WDR19; KIF7; OFD1; IFT52; RPGRIP1L; MKS1; IFT88; IFT122
Intraflagellar transport
IFT-20; KIFAP3A; TTC21B; KIF3C; TTC30B; C11orf60; FLR; DYNLRB1; WDR35; TCTEX1D1
Organelle biogenesis and maintenance
MRPS24; NPHP1; IFT88; TTC8; WDR34; CYS1; MRPS36; KIFAP3B; MRPL46; KIFAP3A
Signal Transduction
RBBP5; RHPN1; PTH2; DEPDC1B; ARHGAP17; ADCYAP1B; SKIA; RAB6A; VIP; PRICKLE1
Signaling by Hedgehog
KIF7; INTU; NOTUM; CDC73; SCUBE2; IFT52; SPOPL; TULP3; WDR35; HHAT