wdr85
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  • Official Full Name
  • WD repeat domain 85
  • Background
  • WDR85 is a WD repeat-containing protein that plays a role in the first step of diphthamide biosynthesis (Carette et;al., 2009 (PubMed 19965467)).
  • Synonyms
  • WDR85; WD repeat domain 85; C9orf112, chromosome 9 open reading frame 112; WD repeat-containing protein 85; FLJ90634; C9orf112; OTTHUMP00000022705; RP11-48C7.3; WDR85_HUMAN
Cat.#:WDR85-330HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human WDR85 293 Cell Lysate
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Involved Pathway

WDR85 involved in several pathways and played different roles in them. We selected most pathways WDR85 participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Metabolism of proteins, Post-translational protein modification, which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR85 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gamma carboxylation, hypusine formation and arylsulfatase activation
OTOP2; DPH3; F9B; ARSK; ARSI; DNAJC24; DPH5; ATPBD4; FURINA; ARSE
Metabolism of proteins
GNE; EEF1D; SAMM50; CNIH2; LTF; MGAT4A; TIMM50; EXOSC8; EEF1A1; IGF2B
Post-translational protein modification
MUC20; TRAPPC5; RING1; SSPO; ARSF; YKT6; SEC22C; ARSJ; GALNT13; ADAMTS1
Synthesis of diphthamide-EEF2
DPH1; DPH5; OTOP2; ATPBD4; DPH3; DPH2; WDR85; DNAJC24

Protein Function

WDR85 has several biochemical functions, for example, diphthine methylesterase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WDR85 itself. We selected most functions WDR85 had, and list some proteins which have the same functions with WDR85. You can find most of the proteins on our site.
Function
Related Protein
Function diphthine methylesterase activity
Related Protein OTOP2; WDR85

Interacting Protein

WDR85 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WDR85 here. Most of them are supplied by our site. Hope this information will be useful for your research of WDR85.
XRCC1; PML; ZBTB33; Dennd6a; Mis12; Chmp4b