wfdc5
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  • Official Full Name
  • WAP four-disulfide core domain 5
  • Background
  • This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
  • Synonyms
  • WFDC5; WAP four-disulfide core domain 5; WAP four-disulfide core domain protein 5; dJ211D12.5; WAP1; p53 responsive gene 5; p53 responsive gene 5 protein; p53-responsive gene 5; p53-responsive gene 5 protein; PRG5; Protease inhibitor WAP1; Putative protease inhibitor WAP1; WAP four disulfide core domain 5
Cat.#:WFDC5-3728HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human WFDC5, GST-tagged
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Cat.#:Wfdc5-1224MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Wfdc5 protein, His & GST-tagged
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Cat.#:Wfdc5-1225RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Wfdc5 protein, His & T7-tagged
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Cat.#:WFDC5-5214RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey WFDC5 Protein, His-tagged
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Cat.#:WFDC5-319HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human WFDC5 293 Cell Lysate
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Protein Function

WFDC5 has several biochemical functions, for example, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WFDC5 itself. We selected most functions WFDC5 had, and list some proteins which have the same functions with WFDC5. You can find most of the proteins on our site.
Function
Related Protein
Function serine-type endopeptidase inhibitor activity
Related Protein SERPINA6; SERPINA1D; SPINK13; A2M; HRG; WFDC6; PTI; SERPINA1; SERPINB1; SERPINA10

WFDC5 Related Articles

Lindquist, JA; Mertens, PR; et al. Myofibroblasts, regeneration or renal fibrosisuis there a decisive hint?. NEPHROLOGY DIALYSIS TRANSPLANTATION 28:2678-2681(2013).
Li, FM; Wang, LL; et al. A double WAP domain-containing protein from Chinese mitten crab Eriocheir sinensis with antimicrobial activities against Gram-negative bacteria and yeast. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 36:183-190(2012).