|Official Full Name||wingless-related MMTV integration site 3|
|Background||Defects in WNT3 are the cause of autosomal recessive tetra-amelia (ARTTRA). Tetra-amelia is a rare human genetic disorder characterized by complete absence of all four limbs and other anomalies such as craniofacial, nervous system, pulmonary, skeletal and urogenital defects.|
|Synonyms||WNT3; wingless-related MMTV integration site 3; Int-4; Wnt-3; proto-oncogene Wnt-3; proto-oncogene Int-4; proto-oncogene protein Wnt-3;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
WNT3 involved in several pathways and played different roles in them. We selected most pathways WNT3 participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Wnt signaling pathway||TCF7; WNT2B; LRP5; SOST; CAMK2D; RAC3; CACYBP; NLK2; PRKCB; PLCB4|
|Hedgehog signaling pathway||GAS1; PRKACAA; IHHB; Shh; GLI2B; PRKACAB; SMO; WNT9A; ZIC2A; IHH|
|Hippo signaling pathway||WNT4; PPP2R2D; WNT1; TCF7; AXIN2; LEF1; WWC1; BMPR1B; WNT8B; GDF7|
|Signaling pathways regulating pluripotency of stem cells||PIK3CG; WNT7B; SKIL; ZFHX3; LIF; MAPK11; WNT9A; FZD7; PAX6; WNT16|
|Melanogenesis||PRKCBA; MITFB; HRASA; RAF1B; CALM1B; GNAIA; EDNRBA; FZD2; PRKCB; PRKACBB|
|HTLV-I infection||TLN1; HLA-DOB; PIK3CG; NFATC3; FZD7; PIK3R5; DLG1; PTTG1; SPI1; HLA-E|
|Pathways in cancer||WNT5A; MSH2; AKT1; LAMB1; CTNNA3; RET; TPR; MAPK9; BAD; FGF1|
|Proteoglycans in cancer||FZD3; PRKCG; WNT4; CAMK2A; Fzd4; ITGB1; MMP2; MAP2K1; PLCG1; VTN|
|MicroRNAs in cancer||PLCG2; TGFB2; ST14; TNC; CCNG1; MMP9; DNMT3B; MDM4; Abcb1b; NOTCH2|
|Basal cell carcinoma||GLI2; TCF7; WNT16; DVL3; BMP4; WNT6; HHIP; SUFU; FZD2; APC|
WNT3 has several biochemical functions, for example, frizzled binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT3 itself. We selected most functions WNT3 had, and list some proteins which have the same functions with WNT3. You can find most of the proteins on our site.
|frizzled binding||NDP; WNT7AA; WNT5A; WNT16; WNT5B; WNT3A; WNT9A; ZNRF3; WNT4A; WNT11|
|protein binding||ABI3; Fzd4; PPIE; HAPLN2; ARMC7; PPAP2B; MAGEE1; SHOC2; LHX9; KRTAP10-11|
|protein domain specific binding||MED12; YWHABA; IST1; CNTROB; YWHAE2; PHRF1; GABRR1; RARA; TWIST2; WNT3A|
|receptor agonist activity||GAS6; VEGFA; WNT4; SFRP2; WNT7A; WNT3; WNT2; NODAL; WNT8A; WNT10B|
WNT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT3.